HitPredict

Interactor 1: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Interactor 2: PLSI (Q14651)
Plastin-1 (Intestine-specific plastin) (I-plastin)
Gene: PLS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~MARCKS
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0032432 - actin filament bundle GO:0051015 - actin filament binding GO:0051017 - actin filament bundle assembly and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 332 Hs			1 629
+	Hs
		164571 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		SPTN2_HUMAN (382-629): 3.19e-49: 187: 21.09
+	Hs
		669987 MARCS_HUMAN (1-322): 2.14e-23: 100: 100.00		SPTB2_HUMAN (382-629): 8.7e-48: 183: 19.53
+	Hs
		993278 TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71		ACTN3_HUMAN (391-626): 2.82e-50: 189: 20.66
+	Hs
		211629 TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71		ACTN4_HUMAN (379-626): 3.78e-49: 186: 19.69
+	Hs
		521586 TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71		ACTN1_HUMAN (378-626): 7.32e-49: 185: 19.61
+	Hs
		725681 TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71		ACTN2_HUMAN (391-626): 2.79e-47: 180: 19.84