Protein: SGK3
Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Cytokine-independent survival kinase) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid-regulated kinase-like)

Gene: SGK3
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q96BR1

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005246 - calcium channel regulator activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1158465

CDC37
Hsp90 co-chaperone Cdc37

2

15

High-throughput

0.811

High

891725

GSK3B
Glycogen synthase kinase-3 beta

2

20

Small-scale

0.800

High

270836

ROCK2
Rho-associated protein kinase 2

1

17

High-throughput

0.691

High

279199

ULK1
Serine/threonine-protein kinase ULK1

1

19

High-throughput

0.691

High

1161853

AMHR2
Anti-Muellerian hormone type-2 receptor

1

3

High-throughput

0.691

High

1384970

SGK2
Serine/threonine-protein kinase Sgk2

1

17

High-throughput

0.691

High

1384974

NISCH
Nischarin

1

5

High-throughput

0.691

High

821751

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.679

High

901468

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.656

High

461792

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

468676

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

831207

CCNF
Cyclin-F

1

9

High-throughput

0.618

High

1384965

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

20

Small-scale

0.607

High

1202110

HS904
Putative heat shock protein HSP 90-alpha A4

1

20

High-throughput

0.575

High

124824

AIP
AH receptor-interacting protein

1

11

High-throughput

0.536

High

476180

ANXA5
Annexin A5

1

5

High-throughput

0.536

High

716333

PRDX6
Peroxiredoxin-6

1

5

High-throughput

0.536

High

861246

MAP1B
Microtubule-associated protein 1B

1

3

High-throughput

0.536

High

876110

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.536

High

895947

F10A1
Hsc70-interacting protein

1

18

High-throughput

0.536

High

957469

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.536

High

1088497

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

2

High-throughput

0.536

High

1124005

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.536

High

1128255

MCM6
DNA replication licensing factor MCM6

1

3

High-throughput

0.536

High

1132885

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.536

High

1384973

NCKP1
Nck-associated protein 1

1

1

High-throughput

0.536

High

568687

GYS1
Glycogen [starch] synthase, muscle

1

0

High-throughput

0.513

High

1211297

DNLZ
DNL-type zinc finger protein

1

0

High-throughput

0.513

High

1384964

PTCD3
Small ribosomal subunit protein mS39

1

0

High-throughput

0.513

High

1384969

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.513

High

1384971

CNBP1
Beta-catenin-interacting protein 1

1

0

High-throughput

0.513

High

1384975

EXOS1
Exosome complex component CSL4

1

0

High-throughput

0.513

High

422826

A4
Amyloid-beta precursor protein

1

10

High-throughput

0.501

High

427925

ICAM1
Intercellular adhesion molecule 1

1

1

High-throughput

0.489

High

712120

CO4A5

1

3

High-throughput

0.489

High

914699

RM12
Large ribosomal subunit protein bL12m

1

3

High-throughput

0.489

High

1104044

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.489

High

1307183

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

12

High-throughput

0.489

High

1311260

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

1

High-throughput

0.489

High

1336563

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

6

High-throughput

0.489

High

1384967

ERP44
Endoplasmic reticulum resident protein 44

1

6

High-throughput

0.489

High

1384968

RM01
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.489

High

332029

KAT7
Histone acetyltransferase KAT7

1

3

High-throughput

0.479

High

1384966

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

20

Small-scale

0.479

High

716390

BLVRB
Flavin reductase

1

0

High-throughput

0.458

High

906440

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

Small-scale

0.458

High

1147093

ELOC
Elongin-C

1

0

High-throughput

0.458

High

1142619

PDK1
[Pyruvate dehydrogenase

1

5

Small-scale

0.445

High

106426

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

941516

CTBP2
C-terminal-binding protein 2

1

6

High-throughput

0.437

High

1277064

CC186
Coiled-coil domain-containing protein 186

1

10

High-throughput

0.437

High

1132515

SMCO1
Single-pass membrane and coiled-coil domain-containing protein 1

1

0

High-throughput

0.292

High

547334

CP19A
Aromatase

1

0

High-throughput

0.279

Low

665657

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.279

Low

869938

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.279

Low

1025736

PURA
Transcriptional activator protein Pur-alpha

1

0

High-throughput

0.279

Low

1038924

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

0

High-throughput

0.279

Low

1136994

SEPT2
Septin-2

1

0

High-throughput

0.279

Low

1275478

TRM1L
tRNA

1

0

High-throughput

0.279

Low

1384972

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025