HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: UBP6 (P43593)
Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.4.19.12) (Deubiquitinating enzyme 6) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6)
Gene: UBP6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37845327
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0072671 - mitochondria-associated ubiquitin-dependent protein catabolic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 499
+	Sc
		676103 MAS5_YEAST (1-352): 2.05e-114: 340: 28.41		UBP6_YEAST (1-495): 5.3e-120: 363: 100.00
+	Hs
		727739 DNJA1_HUMAN (1-352): 1.16e-123: 363: 28.93		UBP14_HUMAN (5-499): 2.66e-104: 322: 29.89
+	Hs
		288354 DNJA1_HUMAN (1-352): 1.16e-123: 363: 28.93		UBP2_HUMAN (79-495): 2.28e-81: 266: 15.79
+	Hs
		728003 DNJA1_HUMAN (1-352): 1.16e-123: 363: 28.93		UBP36_HUMAN (3-496): 1.52e-76: 262: 14.46
+	Hs
		259151 DNJA2_HUMAN (2-352): 3.86e-123: 362: 28.37		UBP36_HUMAN (3-496): 1.52e-76: 262: 14.46
+	Hs
		258679 DNJA2_HUMAN (2-352): 3.86e-123: 362: 28.37		UBP12_HUMAN (69-498): 8.28e-78: 249: 16.48
+	Hs
		727733 DNJA1_HUMAN (1-352): 1.16e-123: 363: 28.93		UBP11_HUMAN (216-499): 5.98e-27: 117: 15.85
+	Mm
		1230427 DJB13_MOUSE (5-352): 1.01e-106: 316: 28.73		UBP7_MOUSE (100-347): 6.71e-30: 126: 21.65