HitPredict

Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008284 - positive regulation of cell population proliferation GO:0019901 - protein kinase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 191
+	Hs
		670920 PRDX3_HUMAN (1-256): 3.48e-122: 349: 100.00		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		545224 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		685658 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436174 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		545338 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		893930 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		436270 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15