Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: PRDX4 (Q13162)
Peroxiredoxin-4 (EC 1.11.1.24) (Antioxidant enzyme AOE372) (AOE37-2) (Peroxiredoxin IV) (Prx-IV) (Thioredoxin peroxidase AO372) (Thioredoxin-dependent peroxide reductase A0372) (Thioredoxin-dependent peroxiredoxin 4)
Gene: PRDX4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 21057456
Identification Methods enzymatic study
Interaction Type oxidoreductase activity electron transfer reaction

The annotation score is based on:

Property Details
Interacting Pfam domains 1-cysPrx_C~Thioredoxin, AhpC-TSA~Thioredoxin
Common GO terms GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0070062 - extracellular exosome
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 505
Hs

1 271
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs

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Last updated: 15 Jul 2024