HitPredict

Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: UBP37 (Q86T82)
Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.4.19.12) (Deubiquitinating enzyme 37) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37)
Gene: USP37

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26299517, 21596315
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0051301 - cell division
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 979
+	Hs
		672789 CDC27_HUMAN (1-824): 0: 625: 100.00		UBP11_HUMAN (242-964): 9.67e-127: 409: 14.30
+	Hs
		1198286 APC7_HUMAN (290-823): 9.27e-61: 217: 16.28		UBP37_HUMAN (1-979): 0: 712: 100.00
+	Hs
		1198285 CDC23_HUMAN (371-823): 1.24e-24: 111: 12.64		UBP37_HUMAN (1-979): 0: 712: 100.00
+	Hs
		1022928 CDC16_HUMAN (391-803): 1.46e-13: 76.5: 10.20		UBP37_HUMAN (1-979): 0: 712: 100.00
+	Mm
		1246852 CDC16_MOUSE (437-803): 6.82e-14: 77.7: 11.14		UBP15_MOUSE (237-955): 5.77e-119: 389: 14.19
+	Hs
		1356120 CDC23_HUMAN (371-823): 1.24e-24: 111: 12.64		UBP22_HUMAN (661-956): 1.53e-36: 147: 13.48