Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: APC4 (Q9UJX5)
Anaphase-promoting complex subunit 4 (APC4) (Cyclosome subunit 4)
Gene: ANAPC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 12956947, 20686030, 26496610, 26811472, 27114510, 32152539, 32076268, 10922056, 35271311, 35952650, 14657031, 22193957, 21926987, 16364912, 21043528, 23007861, 21241890, 24464857, 26083744, 25490258 and 13 others

more...

Identification Methods affinity chromatography technology, pull down, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 824
Hs

1 808
+ Xl
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024