Protein: RRP41
Exosome complex component SKI6 (Extracellular mutant protein 20) (Ribosomal RNA-processing protein 41) (Superkiller protein 6)

Gene: RRP41, SKI6
Organism: Saccharomyces cerevisiae S288C
Interactions: 86
UniProt ID: P46948

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

863136

RRP45
Exosome complex component RRP45

14

20

Small-scale

0.986

High

863145

RRP44
Exosome complex exonuclease DIS3

12

20

Small-scale

0.982

High

863114

RRP46
Exosome complex component RRP46

13

18

Small-scale

0.980

High

863121

CSL4
Exosome complex component CSL4

12

15

Small-scale

0.979

High

804722

RRP4
Exosome complex component RRP4

9

20

Small-scale

0.971

High

672908

RRP43
Exosome complex component RRP43

9

2

Small-scale

0.970

High

863111

MTR3
Exosome complex component MTR3

8

2

Small-scale

0.967

High

863146

RRP40
Exosome complex component RRP40

7

15

Small-scale

0.962

High

863152

RRP6
Exosome complex exonuclease RRP6

15

15

Small-scale

0.760

High

863147

SKI7
Superkiller protein 7

9

9

Small-scale

0.753

High

863154

RRP42
Exosome complex component RRP42

8

20

Small-scale

0.748

High

863131

DHR1
Probable ATP-dependent RNA helicase DHR1

5

3

High-throughput

0.712

High

844511

UTP10
U3 small nucleolar RNA-associated protein 10

4

2

High-throughput

0.691

High

863120

MPP6
M-phase phosphoprotein 6 homolog

3

2

Small-scale

0.664

High

798252

ENP1
Essential nuclear protein 1

3

2

High-throughput

0.640

High

863126

IMA1
Importin subunit alpha

2

2

High-throughput

0.588

High

677460

KRR1
KRR1 small subunit processome component

2

2

High-throughput

0.584

High

863133

UTP14
U3 small nucleolar RNA-associated protein 14

2

3

High-throughput

0.584

High

863141

NOC4
Nucleolar complex protein 4

2

2

High-throughput

0.584

High

527016

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

623883

MYO2
Myosin-2

2

1

High-throughput

0.537

High

863129

SYF1
Pre-mRNA-splicing factor SYF1

1

10

High-throughput

0.508

High

509612

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

684914

DAL80
Nitrogen regulatory protein DAL80

1

0

High-throughput

0.486

High

863124

ADA2
SAGA complex subunit ADA2

1

0

High-throughput

0.486

High

438148

NOT2
General negative regulator of transcription subunit 2

1

1

Small-scale

0.479

High

603073

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

609067

SKI3
Superkiller protein 3

1

4

High-throughput

0.479

High

673196

RRP7
Ribosomal RNA-processing protein 7

1

2

High-throughput

0.479

High

678413

PWP2
Periodic tryptophan protein 2

1

19

High-throughput

0.479

High

707472

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

754299

DCA13
Protein SOF1

1

14

High-throughput

0.479

High

758384

UTP11
U3 small nucleolar RNA-associated protein 11

1

2

High-throughput

0.479

High

763582

UTP20
U3 small nucleolar RNA-associated protein 20

1

2

High-throughput

0.479

High

776605

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.479

High

804935

LRP1
Exosome complex protein LRP1

1

2

High-throughput

0.479

High

806535

UTP9
U3 small nucleolar RNA-associated protein 9

1

2

High-throughput

0.479

High

817588

UTP7
U3 small nucleolar RNA-associated protein 7

1

10

High-throughput

0.479

High

823350

UTP18
U3 small nucleolar RNA-associated protein 18

1

3

High-throughput

0.479

High

826191

FAF1
Protein FAF1

1

2

High-throughput

0.479

High

836181

DIM1
Dimethyladenosine transferase

1

1

High-throughput

0.479

High

863109

MTR4
ATP-dependent RNA helicase DOB1

1

20

High-throughput

0.479

High

863110

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

2

High-throughput

0.479

High

863113

UTP22
U3 small nucleolar RNA-associated protein 22

1

3

High-throughput

0.479

High

863115

UTP8
U3 small nucleolar RNA-associated protein 8

1

2

High-throughput

0.479

High

863118

NRD1
Protein NRD1

1

1

Small-scale

0.479

High

863119

PAP2
Poly(A) RNA polymerase protein 2

1

3

Small-scale

0.479

High

863122

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

863123

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

2

High-throughput

0.479

High

863125

UTP6
U3 small nucleolar RNA-associated protein 6

1

2

High-throughput

0.479

High

863127

UTP17
NET1-associated nuclear protein 1

1

18

High-throughput

0.479

High

863130

UTP5
U3 small nucleolar RNA-associated protein 5

1

19

High-throughput

0.479

High

863132

UTP15
U3 small nucleolar RNA-associated protein 15

1

15

High-throughput

0.479

High

863134

RRP5
rRNA biogenesis protein RRP5

1

8

High-throughput

0.479

High

863135

FCF1
rRNA-processing protein FCF1

1

2

High-throughput

0.479

High

863137

UTP13
U3 small nucleolar RNA-associated protein 13

1

20

High-throughput

0.479

High

863138

UTP21
U3 small nucleolar RNA-associated protein 21

1

19

High-throughput

0.479

High

863139

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

2

High-throughput

0.479

High

863140

RRP9
Ribosomal RNA-processing protein 9

1

19

High-throughput

0.479

High

863142

BFR2
Protein BFR2

1

2

High-throughput

0.479

High

863143

UTP4
U3 small nucleolar RNA-associated protein 4

1

16

High-throughput

0.479

High

863144

RCL1
rRNA processing protein RCL1

1

2

High-throughput

0.479

High

863148

UTP16
U3 small nucleolar RNA-associated protein 16

1

2

High-throughput

0.479

High

863149

BMS1
Ribosome biogenesis protein BMS1

1

2

High-throughput

0.479

High

863150

FCF2
rRNA-processing protein FCF2

1

3

High-throughput

0.479

High

863151

SAS10
Something about silencing protein 10

1

3

High-throughput

0.479

High

863153

UTP12
U3 small nucleolar RNA-associated protein 12

1

20

High-throughput

0.479

High

863155

NOP56
Nucleolar protein 56

1

7

High-throughput

0.479

High

863156

NOP58
Nucleolar protein 58

1

7

High-throughput

0.479

High

863158

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.479

High

863159

NOP14
Nucleolar complex protein 14

1

2

High-throughput

0.479

High

826024

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.460

High

761122

NOT4
General negative regulator of transcription subunit 4

1

0

Small-scale

0.458

High

863116

CF130
Protein CAF130

1

0

Small-scale

0.458

High

863117

COAD
Phosphopantetheine adenylyltransferase

1

0

High-throughput

0.458

High

863128

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

863157

NOT5
General negative regulator of transcription subunit 5

1

0

Small-scale

0.458

High

524362

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

545350

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

781760

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

796421

TRM7
tRNA

1

1

High-throughput

0.417

High

510605

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.407

High

863112

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

3

High-throughput

0.407

High

598360

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.249

Low

624774

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

554707

YPK1
Serine/threonine-protein kinase YPK1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025