Interactor 1: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 12956947, 24811168, 16479161, 23160376, 26963853, 28514442, 12797865, 30498084, 33306668, 33961781, 12097298, 20663873, 18372912, 21986944, 20395298, 23029392, 21241890, 23972993, 21768287, 9734353 and 15 others

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Identification Methods unspecified method, affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
and 4 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 824
Hs

1 496
+ Xl
+ Dm
+ Hs
+ Mm
+ Hs
+ Mm
+ Rn
+ Xl
+ Dm
+ Sc
+ Xl
+ Hs
+ Hs
+ Hs
+ Mm
+ Sc
+ Mm
+ Sp
+ Hs
+ Sc

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Last updated: 15 Jul 2024