Interactor 1: FCERG (P30273)
High affinity immunoglobulin epsilon receptor subunit gamma (Fc receptor gamma-chain) (FcRgamma) (Fc-epsilon RI-gamma) (IgE Fc receptor subunit gamma) (FceRI gamma)
Gene: FCER1G

Interactor 2: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 8071371, 18402654, 34362877, 8663460, 9280292, 8810294
Identification Methods pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, kinase scintillation proximity assay
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002283 - neutrophil activation involved in immune response
GO:0005886 - plasma membrane
GO:0010543 - regulation of platelet activation
GO:0030593 - neutrophil chemotaxis
GO:0031623 - receptor internalization
and 6 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 86
Hs

1 635
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024