Protein: UTP23
rRNA-processing protein UTP23 (U three protein 23) (U3 small nucleolar RNA-associated protein 23) (U3 snoRNA-associated protein 23)

Gene: UTP23
Organism: Saccharomyces cerevisiae S288C
Interactions: 134
UniProt ID: Q12339

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084795

UTP23
rRNA-processing protein UTP23

3

2

Small-scale

0.850

High

1051178

FCF1
rRNA-processing protein FCF1

1

2

Small-scale

0.647

High

150017

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.618

High

677624

KRR1
KRR1 small subunit processome component

2

2

High-throughput

0.614

High

738279

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

2

2

Small-scale

0.595

High

700311

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

2

0

High-throughput

0.588

High

1045130

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.541

High

645566

XRN1
5'-3' exoribonuclease 1

2

1

High-throughput

0.521

High

865196

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

1

Small-scale

0.515

High

673255

RRP7
Ribosomal RNA-processing protein 7

1

2

Small-scale

0.501

High

843290

KRI1
Protein KRI1

1

1

Small-scale

0.501

High

852628

ROK1
ATP-dependent RNA helicase ROK1

1

3

Small-scale

0.501

High

436235

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

512718

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

513287

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

672985

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.479

High

674897

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

682428

SPB4
ATP-dependent rRNA helicase SPB4

1

5

High-throughput

0.479

High

725762

RM09
Large ribosomal subunit protein uL3m

1

2

High-throughput

0.479

High

743794

RML2
Large ribosomal subunit protein uL2m

1

1

High-throughput

0.479

High

747642

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

753656

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

783961

RM07
Large ribosomal subunit protein uL5m

1

2

High-throughput

0.479

High

795946

LSM2
LSM complex subunit LSM2

1

1

High-throughput

0.479

High

798357

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

844666

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

925148

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

1038776

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

1046094

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.479

High

1055529

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

1056500

UTP4
U3 small nucleolar RNA-associated protein 4

1

2

Small-scale

0.479

High

1084796

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.479

High

1084797

NOP56
Nucleolar protein 56

1

3

High-throughput

0.479

High

1084798

RM23
Large ribosomal subunit protein uL13m

1

1

High-throughput

0.479

High

1084799

NOP58
Nucleolar protein 58

1

3

High-throughput

0.479

High

442176

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

514894

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

554655

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.458

High

569523

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.458

High

628185

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.458

High

636697

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.458

High

647948

RM08
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.458

High

648016

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.458

High

657480

RM25
Large ribosomal subunit protein mL59

1

0

High-throughput

0.458

High

666571

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

672570

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.458

High

678223

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.458

High

678626

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.458

High

689727

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

736317

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

736366

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.458

High

747251

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.458

High

778248

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.458

High

778595

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

783834

RM03
Large ribosomal subunit protein mL44

1

0

High-throughput

0.458

High

783904

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.458

High

784029

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.458

High

784078

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.458

High

784147

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

784199

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.458

High

784238

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.458

High

784296

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.458

High

784365

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

784416

RM36
Large ribosomal subunit protein bL31m

1

0

High-throughput

0.458

High

784445

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.458

High

784474

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.458

High

784522

RM40
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.458

High

792651

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.458

High

802450

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

818071

LSM4
LSM complex subunit LSM4

1

0

High-throughput

0.458

High

828569

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.458

High

874594

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

909806

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.458

High

917841

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.458

High

922943

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.458

High

924227

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

924305

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.458

High

924808

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.458

High

1035306

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.458

High

1041445

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.458

High

1046868

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.458

High

1053557

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.458

High

1056311

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

1056480

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.458

High

528052

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

577247

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.445

High

671255

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

755195

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.445

High

811508

XDJ1
DnaJ protein homolog XDJ1

1

2

High-throughput

0.445

High

918861

UTP22
U3 small nucleolar RNA-associated protein 22

1

1

High-throughput

0.445

High

1050214

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.445

High

1053623

MRD1
Multiple RNA-binding domain-containing protein 1

1

1

High-throughput

0.445

High

432740

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.437

High

433907

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

455321

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

503306

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

504477

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

570192

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.437

High

751516

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.437

High

1064831

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

1084488

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.437

High

395021

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

858152

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

525588

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

531934

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.407

High

742710

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

558904

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.305

High

826944

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

383952

RS17A
Small ribosomal subunit protein eS17A

2

0

High-throughput

0.298

High

792314

GBLP
Small ribosomal subunit protein RACK1

2

0

High-throughput

0.298

High

780240

SN114
Pre-mRNA-splicing factor SNU114

1

0

High-throughput

0.282

High

410400

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

435442

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

436551

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

675269

PSB3
Proteasome subunit beta type-3

1

0

High-throughput

0.249

Low

678764

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.249

Low

708569

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

780074

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

795281

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

800868

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.249

Low

812778

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

864145

LSM1
LSM1-LSM7 complex subunit LSM1

1

0

High-throughput

0.249

Low

918499

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

1054015

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1059429

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

1064299

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

365235

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

546796

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low

575539

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

684886

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

804569

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.232

Low

836968

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

893263

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025