HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31980649, 35384245, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 378
+	Hs
		665401 EPHA3_HUMAN (2-831): 0: 646: 19.34		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		872655 EPHA4_HUMAN (2-836): 0: 637: 19.40		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		872447 EPHA5_HUMAN (2-812): 0: 622: 20.39		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		1072507 EPHA7_HUMAN (2-837): 0: 621: 19.50		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		1083031 EPHA6_HUMAN (2-834): 0: 621: 18.25		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		665610 EPHB2_HUMAN (2-837): 0: 605: 19.58		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		665253 EPHA2_HUMAN (3-837): 0: 604: 19.66		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		665480 EPHA8_HUMAN (2-824): 0: 590: 19.20		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		1018328 MERTK_HUMAN (7-861): 0: 588: 40.53		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		600580 EPHA1_HUMAN (1-837): 0: 555: 20.58		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		872537 EPHB4_HUMAN (2-836): 1.08e-180: 549: 20.49		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		972330 TIE2_HUMAN (16-809): 3.58e-164: 510: 23.90		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		725309 TIE1_HUMAN (16-809): 4.24e-158: 494: 21.82		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		411399 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		441514 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		445851 ROS1_HUMAN (284-804): 1.68e-56: 214: 31.27		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		981879 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		983619 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		1079717 Q15850_HUMAN (533-834): 2.4e-59: 211: 37.39		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Mm
		968028 RYK_MOUSE (521-810): 6.88e-58: 211: 36.95		CDC37_MOUSE (1-377): 2.28e-166: 471: 94.97