HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: KANK2 (Q63ZY3)
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25) (Matrix-remodeling-associated protein 3) (SRC-1-interacting protein) (SIP) (SRC-interacting protein) (SRC1-interacting protein)
Gene: KANK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 851
+	Hs
		674564 UFO_HUMAN (1-894): 0: 780: 100.00		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		665591 EPHB2_HUMAN (2-837): 0: 605: 19.58		ANK3_HUMAN (120-791): 9.05e-63: 233: 13.03
+	Hs
		665439 EPHA3_HUMAN (2-831): 0: 646: 19.34		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		665581 EPHB2_HUMAN (2-837): 0: 605: 19.58		ANK2_HUMAN (225-758): 1.22e-49: 192: 12.46
+	Hs
		872504 EPHA5_HUMAN (2-812): 0: 622: 20.39		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		665360 EPHA2_HUMAN (3-837): 0: 604: 19.66		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		310035 EPHA1_HUMAN (1-837): 0: 555: 20.58		TNKS1_HUMAN (393-850): 1.06e-44: 177: 13.28
+	Hs
		600670 EPHA1_HUMAN (1-837): 0: 555: 20.58		TNKS2_HUMAN (671-849): 8.99e-44: 174: 18.30
+	Rn
		94335 INSR_RAT (276-851): 1.26e-134: 437: 27.83		F1M5H6_RAT (48-825): 3.52e-78: 276: 15.98
+	Hs
		600539 EPHA1_HUMAN (1-837): 0: 555: 20.58		DAPK1_HUMAN (658-791): 1.53e-24: 112: 31.34
+	Mm
		103592 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		ANK3_MOUSE (115-851): 1.16e-89: 313: 12.42
+	Hs
		713794 RYK_HUMAN (521-810): 4.45e-57: 209: 37.63		ANK3_HUMAN (120-791): 9.05e-63: 233: 13.03
+	Hs
		713887 RYK_HUMAN (521-810): 4.45e-57: 209: 37.63		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		983635 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		ANKH1_HUMAN (349-849): 1.99e-26: 119: 13.92
+	Hs
		507987 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ASPP2_HUMAN (48-840): 1.69e-69: 251: 15.57
+	Hs
		507971 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ANK3_HUMAN (120-791): 9.05e-63: 233: 13.03
+	Hs
		601612 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		KDIS_HUMAN (659-844): 1.07e-37: 155: 28.04
+	Hs
		507954 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ANK2_HUMAN (225-758): 1.22e-49: 192: 12.46
+	Hs
		507831 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		ANK1_HUMAN (656-850): 2.64e-38: 157: 20.72
+	Hs
		508236 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		RAI14_HUMAN (710-831): 8.96e-21: 100: 27.05