HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: SEPT8 (Q92599)
Septin-8
Gene: SEPTIN8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 483
+	Hs
		674420 UFO_HUMAN (1-894): 0: 780: 100.00		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		665639 EPHB2_HUMAN (2-837): 0: 605: 19.58		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		872498 EPHA5_HUMAN (2-812): 0: 622: 20.39		SEP10_HUMAN (1-429): 0: 582: 72.96
+	Hs
		872441 EPHA5_HUMAN (2-812): 0: 622: 20.39		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		1048994 EPHA7_HUMAN (2-837): 0: 621: 19.50		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		665674 EPHB2_HUMAN (2-837): 0: 605: 19.58		SEP10_HUMAN (1-429): 0: 582: 72.96
+	Hs
		665599 EPHB2_HUMAN (2-837): 0: 605: 19.58		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		411459 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		665678 EPHB2_HUMAN (2-837): 0: 605: 19.58		SEPT9_HUMAN (8-319): 1.86e-155: 455: 39.81
+	Hs
		665677 EPHB2_HUMAN (2-837): 0: 605: 19.58		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40
+	Hs
		713857 RYK_HUMAN (521-810): 4.45e-57: 209: 37.63		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		508127 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		435711 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		508238 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SEP10_HUMAN (1-429): 0: 582: 72.96
+	Hs
		507993 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		435638 IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		508223 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SEP11_HUMAN (11-402): 0: 542: 81.12
+	Hs
		508165 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SEPT5_HUMAN (1-383): 1.04e-170: 486: 36.99
+	Hs
		508253 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SEPT9_HUMAN (8-319): 1.86e-155: 455: 39.81
+	Hs
		508251 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40