Interactor 1: AGTR1 (P30556)
Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor)
Gene: AGTR1
Interactor 2: PF2R (P43088)
Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor)
Gene: PTGFR
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.756 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25512374 |
| Identification Methods | affinity chromatography technology, pull down, protein complementation assay, fluorescent resonance energy transfer |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~7tm_1 |
| Common GO terms | GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0007186 - G protein-coupled receptor signaling pathway GO:0007204 - positive regulation of cytosolic calcium ion concentration |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
