HitPredict

Interactor 1: PSB5 (P30656)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit PRE2) (Multicatalytic endopeptidase complex subunit PRE2) (Proteasome component PRE2) (Proteinase YSCE subunit PRE2)
Gene: PRE2

Interactor 2: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25311859
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 287 Sc			1 398
+	Hs
		656184 PSA5_HUMAN (50-275): 2.82e-83: 252: 16.74		RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50
+	Hs
		872245 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50
+	Hs
		638096 PSA4_HUMAN (52-272): 5.75e-82: 249: 15.88		RD23B_HUMAN (2-398): 5.1e-90: 279: 27.50
+	Hs
		656183 PSA5_HUMAN (50-275): 2.82e-83: 252: 16.74		RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09
+	Hs
		872130 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09
+	Hs
		638095 PSA4_HUMAN (52-272): 5.75e-82: 249: 15.88		RD23A_HUMAN (2-398): 3.37e-87: 270: 28.09
+	Hs
		656337 PSA5_HUMAN (50-275): 2.82e-83: 252: 16.74		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		893771 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53
+	Hs
		656327 PSA5_HUMAN (50-275): 2.82e-83: 252: 16.74		UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65
+	Hs
		893768 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		UBQL2_HUMAN (1-373): 8.68e-55: 192: 12.65
+	Hs
		656323 PSA5_HUMAN (50-275): 2.82e-83: 252: 16.74		UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76
+	Hs
		893761 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		UBQL4_HUMAN (2-373): 1.16e-52: 186: 13.76
+	Dm
		1178971 Q7K148_DROME (8-280): 5.92e-83: 252: 46.93		Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38
+	Dm
		1278653 PSA5_DROME (50-276): 1.74e-83: 252: 16.94		Q9VWD9_DROME (2-374): 1.81e-47: 171: 13.38
+	Hs
		893645 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73
+	Hs
		474931 PSA4_HUMAN (52-272): 5.75e-82: 249: 15.88		UBB_HUMAN (2-77): 3.63e-35: 131: 23.68
+	Hs
		656197 PSA5_HUMAN (50-275): 2.82e-83: 252: 16.74		RL40_HUMAN (2-68): 1.02e-16: 77.7: 26.87
+	Hs
		893646 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		RL40_HUMAN (2-68): 1.02e-16: 77.7: 26.87
+	Hs
		656238 PSA5_HUMAN (50-275): 2.82e-83: 252: 16.74		NEDD8_HUMAN (2-62): 2.68e-15: 72.3: 24.59
+	Hs
		893676 PSA6_HUMAN (44-279): 9.65e-83: 250: 14.52		NEDD8_HUMAN (2-62): 2.68e-15: 72.3: 24.59