Interactor 1: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Interactor 2: SLD5 (Q03406)
DNA replication complex GINS protein SLD5
Gene: SLD5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 24805245, 16531994, 25313033, 32804080, 32075754, 27397685, 19661920, 19913425, 37968396, 21362622, 21868389, 22433841, 23499531
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, biochemical, pull down, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~Sld5, MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
GO:0031261 - DNA replication preinitiation complex
GO:0031298 - replication fork protection complex
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 933
Sc

1 294
+ Sc
+ Sc
+ Sc
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Mm
+ Mm
+ Dm
+ Hs
+ Sc

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Last updated: 15 Jul 2024