HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: NUP49 (Q02199)
Nucleoporin NUP49/NSP49 (Nuclear pore protein NUP49/NSP49)
Gene: NUP49

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.648

Property	Details
Experiments	11387327, 9368759, 18573877
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000055 - ribosomal large subunit export from nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Sc			1 472
+	Hs
		162244 XPO1_HUMAN (3-1084): 0: 854: 46.40		GANP_HUMAN (3-461): 1.32e-46: 175: 14.31
+	Hs
		163216 XPO1_HUMAN (3-1084): 0: 854: 46.40		NUP58_HUMAN (22-450): 7.28e-33: 133: 15.44
+	Hs
		162539 XPO1_HUMAN (3-1084): 0: 854: 46.40		SC24C_HUMAN (4-278): 4.23e-31: 129: 14.75
+	Hs
		162534 XPO1_HUMAN (3-1084): 0: 854: 46.40		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		162517 XPO1_HUMAN (3-1084): 0: 854: 46.40		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Hs
		162448 XPO1_HUMAN (3-1084): 0: 854: 46.40		NU214_HUMAN (9-247): 6.29e-16: 82.9: 22.39
+	Sc
		676198 XPO1_YEAST (1-1084): 0: 833: 100.00		NU145_YEAST (1-351): 5.19e-20: 95.7: 16.76
+	Sc
		676300 XPO1_YEAST (1-1084): 0: 833: 100.00		NU100_YEAST (1-363): 1.45e-17: 87.9: 20.00
+	Sc
		676195 XPO1_YEAST (1-1084): 0: 833: 100.00		NUP57_YEAST (17-256): 3.28e-17: 85.9: 32.67
+	Sc
		676117 XPO1_YEAST (1-1084): 0: 833: 100.00		NU159_YEAST (2-419): 1.68e-10: 65.6: 12.88
+	Sc
		676301 XPO1_YEAST (1-1084): 0: 833: 100.00		NU116_YEAST (1-276): 9.6e-09: 59.8: 20.85
+	Tt
		101847 G0RZB7_CHATD (10-1084): 0: 779: 50.19		NU145_CHATD (18-328): 2.36e-10: 65.2: 20.67
+	Hs
		834682 XPO7_HUMAN (11-1030): 8.18e-147: 469: 13.59		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Hs
		727340 TNPO3_HUMAN (8-1040): 5.86e-127: 412: 13.31		NU214_HUMAN (9-247): 6.29e-16: 82.9: 22.39
+	Hs
		858024 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		834652 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Hs
		727300 TNPO1_HUMAN (21-967): 5.08e-125: 406: 12.09		NU214_HUMAN (9-247): 6.29e-16: 82.9: 22.39
+	Hs
		155553 TNPO2_HUMAN (21-956): 4.51e-116: 382: 11.98		NUP98_HUMAN (124-327): 9.57e-18: 88.7: 14.67
+	Hs
		155550 TNPO2_HUMAN (21-956): 4.51e-116: 382: 11.98		NU153_HUMAN (1-243): 4.4e-17: 86.7: 18.00
+	Ce
		248176 O62332_CAEEL (10-967): 2.56e-97: 330: 11.48		Q21295_CAEEL (53-210): 4.88e-11: 67.1: 18.45