Protein: PDPK1
3-phosphoinositide-dependent protein kinase 1 (dPDK-1) (EC 2.7.11.1) (Serine/threonine-protein kinase 61C) (dSTPK61)

Gene: PDPK1, Pdk1
Organism: Drosophila melanogaster
Interactions: 121
UniProt ID: Q9W0V1

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004676 - 3-phosphoinositide-dependent protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1269059

Q7KSP5
Lethal

1

1

High-throughput

0.621

High

264542

O62602
mitogen-activated protein kinase kinase

1

19

High-throughput

0.618

High

834830

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

3

High-throughput

0.618

High

921008

ACT3
Actin-57B

1

14

High-throughput

0.618

High

929314

KC1A
Casein kinase I isoform alpha

1

18

High-throughput

0.618

High

1064258

SQD
RNA-binding protein squid

1

9

High-throughput

0.618

High

1176061

DJTID
DnaJ homolog l(2)tid, mitochondrial

1

8

High-throughput

0.618

High

1269980

Q7KV89
Mitogen-activated protein kinase kinase kinase kinase

1

20

High-throughput

0.618

High

1470161

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

6

High-throughput

0.618

High

1474163

Q9VFV9
DnaJ-like-2, isoform A

1

12

High-throughput

0.618

High

1476138

Q9VHC7
FI21236p1

1

7

High-throughput

0.618

High

1483453

DJSHV
DnaJ homolog shv

1

10

High-throughput

0.618

High

1488422

Q9VXR3
HECT-type E3 ubiquitin transferase

1

20

High-throughput

0.618

High

1488429

Q9VXR5
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.618

High

1344856

Q8SZN9
Lethal

1

1

High-throughput

0.590

High

95273

E1JIH4
Uncharacterized protein, isoform D

1

0

High-throughput

0.586

High

1019323

P91656
Ribosomal protein S6 kinase

1

17

High-throughput

0.492

High

1174423

Q24496
non-specific serine/threonine protein kinase

1

18

High-throughput

0.492

High

1303759

AKT1
RAC serine/threonine-protein kinase

1

17

High-throughput

0.492

High

1474019

Q9VFP5
Kotsubu

1

0

High-throughput

0.486

High

1489490

Q9W4J8
FI24210p1

1

0

High-throughput

0.486

High

95445

E1JJN5
Uncharacterized protein, isoform D

1

11

High-throughput

0.481

High

56565

CLU
Protein clueless

1

3

High-throughput

0.479

High

56745

A1ZAH8
40S ribosomal protein S15

1

1

High-throughput

0.479

High

57313

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

4

High-throughput

0.479

High

84951

B7Z0X1
Serine hydroxymethyltransferase

1

2

High-throughput

0.479

High

92135

D2A6L8
Flagrante delicto Y, isoform D

1

6

High-throughput

0.479

High

94930

E1JGL8
Uncharacterized protein, isoform C

1

2

High-throughput

0.479

High

94973

E1JGN7
Heterogeneous nuclear ribonucleoprotein K, isoform E

1

9

High-throughput

0.479

High

120887

M9PEE1
Smallminded, isoform H

1

18

High-throughput

0.479

High

120973

M9PEH8
Fiery mountain, isoform D

1

3

High-throughput

0.479

High

198114

PRS8
26S proteasome regulatory subunit 8

1

13

High-throughput

0.479

High

198196

GBLP
Small ribosomal subunit protein RACK1

1

10

High-throughput

0.479

High

262641

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

263502

O61380
Eukaryotic translation initiation factor 4G1, isoform A

1

3

High-throughput

0.479

High

471523

RLA1
Large ribosomal subunit protein P1

1

2

High-throughput

0.479

High

476490

TBB3
Tubulin beta-3 chain

1

18

High-throughput

0.479

High

554109

TCPA
T-complex protein 1 subunit alpha

1

14

High-throughput

0.479

High

618812

DDX17
ATP-dependent RNA helicase p62

1

7

High-throughput

0.479

High

633084

NCD
Protein claret segregational

1

3

High-throughput

0.479

High

652133

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

8

High-throughput

0.479

High

715182

CLH
Clathrin heavy chain

1

3

High-throughput

0.479

High

715386

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.479

High

773399

RFC1
Replication factor C subunit 1

1

6

High-throughput

0.479

High

782832

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

6

High-throughput

0.479

High

822385

METK
S-adenosylmethionine synthase

1

1

High-throughput

0.479

High

875048

PRS4
26S proteasome regulatory subunit 4

1

14

High-throughput

0.479

High

939583

RS9
Small ribosomal subunit protein uS4

1

2

High-throughput

0.479

High

1038267

IF4A
Eukaryotic initiation factor 4A

1

16

High-throughput

0.479

High

1070037

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.479

High

1262248

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.479

High

1266283

Q7K485
Cathepsin D

1

1

High-throughput

0.479

High

1267138

Q7KHK9
DREAM

1

8

High-throughput

0.479

High

1267762

Q7KMQ0
26S proteasome regulatory subunit 7

1

13

High-throughput

0.479

High

1268057

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

15

High-throughput

0.479

High

1285721

Q86BM5
A kinase anchor protein 200, isoform D

1

8

High-throughput

0.479

High

1321385

Q8MST5
Tubulin beta chain

1

18

High-throughput

0.479

High

1345678

RS23
Small ribosomal subunit protein uS12

1

1

High-throughput

0.479

High

1375229

Q94883
DNA replication-related element factor, isoform A

1

1

High-throughput

0.479

High

1377301

Q95RE4
LD37574p

1

6

High-throughput

0.479

High

1377942

KCMF1
E3 ubiquitin-protein ligase Kcmf1

1

4

High-throughput

0.479

High

1378518

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

3

High-throughput

0.479

High

1463437

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.479

High

1464493

Q9V3V6
26S proteasome regulatory complex subunit p50

1

20

High-throughput

0.479

High

1464903

Q9V405
26S proteasome regulatory subunit 6B

1

11

High-throughput

0.479

High

1465654

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

3

High-throughput

0.479

High

1466795

Q9V9Q4
LD43819p

1

3

High-throughput

0.479

High

1467553

RS7
Small ribosomal subunit protein eS7

1

2

High-throughput

0.479

High

1468512

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

2

High-throughput

0.479

High

1468556

LARP
La-related protein 1

1

11

High-throughput

0.479

High

1469793

Q9VBX3
Vig2, isoform B

1

6

High-throughput

0.479

High

1470424

NUP98
Nuclear pore complex protein Nup98-Nup96

1

6

High-throughput

0.479

High

1475020

IPO9
Importin-9

1

10

High-throughput

0.479

High

1476515

Q9VHN7
transketolase

1

5

High-throughput

0.479

High

1479451

NFS1
Cysteine desulfurase, mitochondrial

1

5

High-throughput

0.479

High

1482304

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

20

High-throughput

0.479

High

1485459

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

1486913

AGO2
Protein argonaute-2

1

1

High-throughput

0.479

High

1487642

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

4

High-throughput

0.479

High

1487948

Q9VWL0
Mec2

1

7

High-throughput

0.479

High

1487956

Q9VWL9
LD25711p

1

6

High-throughput

0.479

High

1488407

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

12

High-throughput

0.479

High

1489486

DCAF1
Protein mahjong

1

3

High-throughput

0.479

High

1489488

Q9W414
Regulatory particle triple-A ATPase 4

1

13

High-throughput

0.479

High

1489491

Q9Y162
vesicle-fusing ATPase

1

11

High-throughput

0.479

High

1303353

SPT2
Protein SPT2 homolog

1

7

High-throughput

0.464

High

1466703

NUBPL
Iron-sulfur cluster transfer protein Nubpl

1

0

High-throughput

0.458

High

1467294

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.458

High

1480688

Q9VLC5
aldehyde dehydrogenase

1

0

High-throughput

0.458

High

1019963

1433E
14-3-3 protein epsilon

1

12

High-throughput

0.457

High

145795

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

11

High-throughput

0.437

High

264460

O62530
Adaptor protein complex 2, mu subunit, isoform A

1

4

High-throughput

0.437

High

607520

RS17
Small ribosomal subunit protein eS17

1

2

High-throughput

0.437

High

710965

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.437

High

870559

RS15A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

898310

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.437

High

1264058

NUP50
Nuclear pore complex protein Nup50

1

2

High-throughput

0.437

High

1344561

Q8SYL1
Glutamate-rich WD repeat-containing protein 1

1

4

High-throughput

0.437

High

1466042

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.437

High

1469355

Q9VBN5
60S ribosomal protein L27

1

1

High-throughput

0.437

High

1477638

EFNMT
eEF1A lysine and N-terminal methyltransferase homolog [Includes: eEF1A lysine methyltransferase homolog

1

2

High-throughput

0.437

High

1478338

Q9VJD1
Glucosidase 2 subunit beta

1

1

High-throughput

0.437

High

1482204

Q9VMX4
AT19154p

1

3

High-throughput

0.437

High

1484368

Q9VQL7
Fatty acid synthase

1

4

High-throughput

0.437

High

1487007

Q9VUZ0
Translocon-associated protein subunit beta

1

1

High-throughput

0.437

High

1487149

Q9VV75
AT02348p

1

3

High-throughput

0.437

High

1487478

Q9VVU2
GEO07453p1

1

2

High-throughput

0.437

High

1488250

Q9VXH4
RE16337p

1

1

High-throughput

0.437

High

1489146

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.437

High

1489484

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.437

High

1489485

RS16
Small ribosomal subunit protein uS9

1

3

High-throughput

0.437

High

1489487

Q9W335
Translocon-associated protein subunit alpha

1

2

High-throughput

0.437

High

1489489

Q9W4C1
IP13321p

1

1

High-throughput

0.437

High

1302842

Q8IH13
LD21452p

1

0

High-throughput

0.265

Low

1469302

MS57A
Accessory gland-specific peptide 57Da

1

0

High-throughput

0.265

Low

559183

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.249

Low

832206

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.249

Low

1343656

Q8SX89
Kugelkern, isoform A

1

0

High-throughput

0.249

Low

1481241

Q9VLT7
IP17351p

1

0

High-throughput

0.249

Low

1482669

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.249

Low

1489483

Q9W1N3
Levy, isoform A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025