Protein: RHG01
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP)

Gene: RHG01, ARHGAP1
Organism: Homo sapiens
Interactions: 165
UniProt ID: Q07960

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007264 - small GTPase-mediated signal transduction
GO:0007266 - Rho protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

893937

CDC42
Cell division control protein 42 homolog

11

20

Small-scale

0.976

High

900412

RHOA
Transforming protein RhoA

9

20

Small-scale

0.972

High

993017

BNIP2
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

3

10

Small-scale

0.871

High

436273

RHOC
Rho-related GTP-binding protein RhoC

3

20

High-throughput

0.860

High

925227

RAC1
Ras-related C3 botulinum toxin substrate 1

3

20

Small-scale

0.849

High

350113

RASK
GTPase KRas

2

14

High-throughput

0.754

High

591826

RAB4A
Ras-related protein Rab-4A

2

6

High-throughput

0.754

High

914029

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.754

High

915629

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

950946

RHOG
Rho-related GTP-binding protein RhoG

2

20

Small-scale

0.737

High

993032

SRGP1
SLIT-ROBO Rho GTPase-activating protein 1

2

14

High-throughput

0.737

High

993060

FSD1
Fibronectin type III and SPRY domain-containing protein 1

3

16

High-throughput

0.667

High

655336

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

18

Small-scale

0.647

High

993015

RHG01
Rho GTPase-activating protein 1

1

14

Small-scale

0.647

High

993041

FBX25
F-box only protein 25

3

0

High-throughput

0.638

High

361858

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

1

High-throughput

0.628

High

993029

SETX
Probable helicase senataxin

2

1

High-throughput

0.628

High

993054

CDK15
Cyclin-dependent kinase 15

2

1

High-throughput

0.628

High

993031

BNIPL
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein

1

10

Small-scale

0.621

High

120405

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

318116

DIRA3
GTP-binding protein Di-Ras3

1

5

High-throughput

0.618

High

348636

RASN
GTPase NRas

1

14

High-throughput

0.618

High

545341

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564492

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

591554

RAB3B
Ras-related protein Rab-3B

1

3

High-throughput

0.618

High

592223

RAB5A
Ras-related protein Rab-5A

1

5

High-throughput

0.618

High

844497

RAB5C
Ras-related protein Rab-5C

1

5

High-throughput

0.618

High

845451

RAB9A
Ras-related protein Rab-9A

1

5

High-throughput

0.618

High

852450

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

884477

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.618

High

892334

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

895053

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.618

High

993020

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.618

High

993021

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

993069

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

993071

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

993026

FOXR2
Forkhead box protein R2

3

2

High-throughput

0.609

High

993058

SH3G1
Endophilin-A2

2

20

High-throughput

0.606

High

227266

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

338327

EGFR
Epidermal growth factor receptor

2

15

High-throughput

0.584

High

506986

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

331262

CHK2
Serine/threonine-protein kinase Chk2

1

3

High-throughput

0.541

High

125995

UPK1A
Uroplakin-1a

1

3

High-throughput

0.536

High

565916

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.536

High

686647

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

817966

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.536

High

958664

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.536

High

993062

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

8

High-throughput

0.536

High

675827

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.513

High

739959

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.513

High

882722

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

993050

PRR11
Proline-rich protein 11

1

0

High-throughput

0.513

High

993073

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

993092

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

174826

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

522938

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.501

High

993039

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.489

High

993087

PHF11
PHD finger protein 11

1

2

High-throughput

0.489

High

993091

NTNG1
Netrin-G1

1

2

High-throughput

0.489

High

162665

XPO1
Exportin-1

1

11

High-throughput

0.479

High

163796

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

178499

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

212807

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

322521

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

364254

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

390194

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.479

High

411366

INSR
Insulin receptor

1

18

High-throughput

0.479

High

503962

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

507962

FGFR1
Fibroblast growth factor receptor 1

1

14

High-throughput

0.479

High

521888

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

527421

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.479

High

567026

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

573669

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

648738

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.479

High

654282

CALX
Calnexin

1

1

High-throughput

0.479

High

726170

BASI
Basigin

1

4

High-throughput

0.479

High

742250

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

847450

BAP31
B-cell receptor-associated protein 31

1

2

High-throughput

0.479

High

890119

SC61B
Protein transport protein Sec61 subunit beta

1

4

High-throughput

0.479

High

912870

ARF6
ADP-ribosylation factor 6

1

8

High-throughput

0.479

High

940407

CXAR
Coxsackievirus and adenovirus receptor

1

4

High-throughput

0.479

High

965645

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

974779

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

990421

CKAP4
Cytoskeleton-associated protein 4

1

9

High-throughput

0.479

High

993016

STX4
Syntaxin-4

1

3

High-throughput

0.479

High

993025

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

993028

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

993033

TM11B
Transmembrane protease serine 11B

1

5

High-throughput

0.479

High

993034

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

High-throughput

0.479

High

993035

TAXB1
Tax1-binding protein 1

1

7

High-throughput

0.479

High

993040

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

993042

BICD2
Protein bicaudal D homolog 2

1

12

High-throughput

0.479

High

993044

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

993047

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

993057

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

993072

ANLN
Anillin

1

2

High-throughput

0.479

High

993077

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.479

High

993080

ARL15
ADP-ribosylation factor-like protein 15

1

12

High-throughput

0.479

High

993083

ANFY1
Rabankyrin-5

1

6

High-throughput

0.479

High

993085

TES
Testin

1

1

High-throughput

0.479

High

993086

XPO7
Exportin-7

1

9

High-throughput

0.479

High

993090

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

825685

MTR1B
Melatonin receptor type 1B

1

3

High-throughput

0.464

High

198250

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.458

High

670000

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

785878

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

825398

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

838790

EMD
Emerin

1

0

High-throughput

0.458

High

993024

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

993049

TECT2
Tectonic-2

1

0

High-throughput

0.458

High

993064

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

993068

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

993070

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

993074

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

993078

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

993082

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

993088

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.458

High

993093

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

56610

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

4

High-throughput

0.445

High

905853

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

5

High-throughput

0.445

High

993018

STK4
Serine/threonine-protein kinase 4

1

4

High-throughput

0.445

High

205310

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

305425

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

390848

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

435622

IGF1R
Insulin-like growth factor 1 receptor

1

18

High-throughput

0.437

High

525915

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.437

High

552570

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

607950

FGFR4
Fibroblast growth factor receptor 4

1

16

High-throughput

0.437

High

651038

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

720306

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

993022

NTRK3
NT-3 growth factor receptor

1

16

High-throughput

0.437

High

993023

OCLN
Occludin

1

2

High-throughput

0.437

High

993030

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.437

High

993038

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.437

High

993052

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.437

High

993059

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.437

High

993066

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.437

High

993076

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.437

High

993094

MTCH2
Mitochondrial carrier homolog 2

1

4

High-throughput

0.437

High

993051

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

993037

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

993048

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

993053

FA81B
Protein FAM81B

1

0

High-throughput

0.279

Low

993063

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

993027

ATRAP
Type-1 angiotensin II receptor-associated protein

1

0

High-throughput

0.265

Low

132459

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

329674

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

795110

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

961638

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

993019

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

993036

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

993043

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low

993045

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.249

Low

993046

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

993055

PANX1
Pannexin-1

1

0

High-throughput

0.249

Low

993056

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

993061

DERL1
Derlin-1

1

0

High-throughput

0.249

Low

993065

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low

993067

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

993075

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

993079

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

993081

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

993084

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.249

Low

993089

CLC4E
C-type lectin domain family 4 member E

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024