HitPredict

Interactor 1: DLG4 (P31016)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: KCJ12 (P52188)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: Kcnj12

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15024025
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030165 - PDZ domain binding GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Rn			1 427
+	Hs
		942342 DLG4_HUMAN (1-724): 0: 676: 99.86		KCJ12_HUMAN (1-427): 0: 741: 96.07
+	Hs
		929762 DLG4_HUMAN (1-724): 0: 676: 99.86		KCNJ2_HUMAN (6-427): 0: 699: 70.82
+	Hs
		1054724 DLG3_HUMAN (28-724): 0: 603: 64.37		KCJ12_HUMAN (1-427): 0: 741: 96.07
+	Rn
		852399 DLG3_RAT (9-724): 0: 595: 62.80		KCJ12_RAT (1-427): 0: 747: 100.00
+	Hs
		1021490 DLG1_HUMAN (28-724): 0: 580: 72.65		KCJ12_HUMAN (1-427): 0: 741: 96.07
+	Hs
		80982 DLG1_HUMAN (28-724): 0: 580: 72.65		KCJ18_HUMAN (1-427): 0: 732: 94.69
+	Rn
		852397 DLG1_RAT (5-724): 0: 565: 69.13		KCJ12_RAT (1-427): 0: 747: 100.00
+	Hs
		929764 DLG1_HUMAN (28-724): 0: 580: 72.65		KCNJ2_HUMAN (6-427): 0: 699: 70.82
+	Rn
		1144015 DLG1_RAT (5-724): 0: 565: 69.13		KCNJ2_RAT (6-427): 0: 695: 70.82
+	Mm
		852403 DLG4_MOUSE (1-724): 0: 676: 99.45		KCNJ4_MOUSE (32-427): 0: 574: 62.73
+	Hs
		816146 DLG4_HUMAN (1-724): 0: 676: 99.86		KCNJ4_HUMAN (31-427): 0: 571: 62.81
+	Mm
		1143540 DLG4_MOUSE (1-724): 0: 676: 99.45		Q9QYK8_MOUSE (39-386): 0: 562: 70.38
+	Mm
		291382 DLG4_MOUSE (1-724): 0: 676: 99.45		KCNJ1_MOUSE (39-358): 1.39e-172: 489: 49.85
+	Hs
		816147 DLG1_HUMAN (28-724): 0: 580: 72.65		KCNJ4_HUMAN (31-427): 0: 571: 62.81
+	Mm
		1143568 DLG4_MOUSE (1-724): 0: 676: 99.45		KCJ16_MOUSE (36-363): 5.94e-164: 469: 49.09
+	Mm
		1143532 DLG4_MOUSE (1-724): 0: 676: 99.45		KCJ10_MOUSE (43-354): 1.24e-159: 456: 44.59
+	Hs
		816159 DLG1_HUMAN (28-724): 0: 580: 72.65		KCNJ6_HUMAN (40-381): 0: 527: 52.92
+	Hs
		929767 SCRIB_HUMAN (58-243): 6.07e-25: 113: 40.72		KCNJ2_HUMAN (6-427): 0: 699: 70.82
+	Hs
		816149 SCRIB_HUMAN (58-243): 6.07e-25: 113: 40.72		KCNJ4_HUMAN (31-427): 0: 571: 62.81
+	Dm
		677699 DLG1_DROME (22-322): 2.17e-26: 117: 19.21		Q8IGY2_DROME (18-364): 4.33e-175: 498: 49.01