Protein: HSF4
Heat shock factor protein 4 (HSF 4) (hHSF4) (Heat shock transcription factor 4) (HSTF 4)

Gene: HSF4
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q9ULV5

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

961319

HSF1
Heat shock factor protein 1

2

17

High-throughput

0.811

High

977937

HSF2
Heat shock factor protein 2

2

17

High-throughput

0.811

High

270842

FOXH1
Forkhead box protein H1

2

2

High-throughput

0.606

High

881834

SOX10
Transcription factor SOX-10

2

1

High-throughput

0.606

High

1021268

FOXI1
Forkhead box protein I1

2

1

High-throughput

0.606

High

1357071

AKP8L
A-kinase anchor protein 8-like

2

1

High-throughput

0.606

High

204456

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

941969

PITX1
Pituitary homeobox 1

2

0

High-throughput

0.580

High

1135542

INT11
Integrator complex subunit 11

2

0

High-throughput

0.580

High

647709

MK03
Mitogen-activated protein kinase 3

1

8

Small-scale

0.578

High

659088

MK01
Mitogen-activated protein kinase 1

1

8

Small-scale

0.578

High

1313490

DUS26
Dual specificity protein phosphatase 26

1

0

Small-scale

0.561

High

847114

SMCA4
Transcription activator BRG1

1

5

Small-scale

0.561

High

1354568

DAXX
Death domain-associated protein 6

1

1

Small-scale

0.561

High

160225

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

1

High-throughput

0.553

High

280928

KRT37
Keratin, type I cuticular Ha7

2

3

High-throughput

0.553

High

281081

KRT38
Keratin, type I cuticular Ha8

2

3

High-throughput

0.553

High

419081

TPM3
Tropomyosin alpha-3 chain

2

4

High-throughput

0.553

High

740276

NUP62
Nuclear pore glycoprotein p62

2

7

High-throughput

0.553

High

1023581

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

2

High-throughput

0.553

High

1071444

K1H1
Keratin, type I cuticular Ha1

2

3

High-throughput

0.553

High

1149400

K1C40
Keratin, type I cytoskeletal 40

2

3

High-throughput

0.553

High

1242081

LIPB2
Liprin-beta-2

2

1

High-throughput

0.553

High

1317046

YTHD1
YTH domain-containing family protein 1

2

1

High-throughput

0.553

High

1357072

SGT1
Protein SGT1 homolog

1

2

High-throughput

0.536

High

781482

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.513

High

1033066

TARB1
Probable methyltransferase TARBP1

1

0

High-throughput

0.513

High

1035045

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.489

High

1070188

RABE1
Rab GTPase-binding effector protein 1

1

1

High-throughput

0.489

High

215058

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.486

High

279823

CDKA2
Cyclin-dependent kinase 2-associated protein 2

1

0

High-throughput

0.486

High

575622

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

1202612

SESD1
SEC14 domain and spectrin repeat-containing protein 1

4

0

High-throughput

0.364

High

49979

F168B
Myelin-associated neurite-outgrowth inhibitor

2

0

High-throughput

0.316

High

180761

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

474670

NHLC4
NHL-repeat-containing protein 4

2

0

High-throughput

0.316

High

1109279

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1109424

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1110451

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.316

High

1124854

ACTMP
Actin maturation protease

2

0

High-throughput

0.316

High

1132002

CJ055
Uncharacterized protein C10orf55

2

0

High-throughput

0.316

High

1156844

UFSP1
Inactive Ufm1-specific protease 1

2

0

High-throughput

0.316

High

1262341

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

1317384

KRA31
Keratin-associated protein 3-1

2

0

High-throughput

0.316

High

1327473

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1347905

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

2

0

High-throughput

0.316

High

1346481

FBX28
F-box only protein 28

1

0

High-throughput

0.279

Low

1356533

MYO15
Unconventional myosin-XV

1

0

High-throughput

0.279

Low

1357073

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.279

Low

1223904

F200C
Protein FAM200C

1

0

High-throughput

0.265

Low

1348109

ALKB4
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

1

0

Small-scale

0.265

Low


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Last updated: 15 Jul 2024