HitPredict

Interactor 1: SDHA (P31040)
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (Fp)
Gene: SDHA

Interactor 2: SDHF2 (Q9NX18)
Succinate dehydrogenase assembly factor 2, mitochondrial (SDH assembly factor 2) (SDHAF2)
Gene: SDHAF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 26496610, 28514442, 33961781, 19628817
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FAD_binding_2~Sdh5, Sdh5~Succ_DH_flav_C
Common GO terms GO:0005730 - nucleolus
GO:0005739 - mitochondrion
GO:0006099 - tricarboxylic acid cycle
GO:0006121 - mitochondrial electron transport, succinate to ubiquinone
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 664
Hs

1 166
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024