HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: RAB34 (Q9BZG1)
Ras-related protein Rab-34 (Ras-related protein Rab-39) (Ras-related protein Rah)
Gene: RAB34

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26496610, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 259
+	Hs
		678358 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB35_HUMAN (52-258): 4.84e-86: 256: 34.78
+	Hs
		678344 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1A_HUMAN (43-258): 1.57e-84: 252: 30.56
+	Mm
		838709 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (43-258): 1.57e-84: 252: 30.56
+	Hs
		678394 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (45-258): 2.9e-82: 246: 30.84
+	Hs
		678359 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11B_HUMAN (46-258): 5.11e-81: 244: 27.57
+	Hs
		678343 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (46-258): 1.04e-80: 243: 27.23
+	Hs
		838645 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB35_HUMAN (52-258): 4.84e-86: 256: 34.78
+	Hs
		838625 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (43-258): 1.57e-84: 252: 30.56
+	Hs
		838683 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1B_HUMAN (45-258): 2.9e-82: 246: 30.84
+	Hs
		838647 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11B_HUMAN (46-258): 5.11e-81: 244: 27.57
+	Hs
		838624 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (46-258): 1.04e-80: 243: 27.23
+	Hs
		678333 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB13_HUMAN (54-258): 3.36e-37: 131: 37.56
+	Hs
		678341 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB14_HUMAN (52-218): 2.18e-34: 124: 37.73
+	Hs
		678402 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB6B_HUMAN (54-214): 6.33e-34: 123: 39.13
+	Hs
		592631 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB6A_HUMAN (54-239): 1.98e-33: 122: 36.56
+	Hs
		838608 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB13_HUMAN (54-258): 3.36e-37: 131: 37.56
+	Hs
		838621 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB14_HUMAN (52-218): 2.18e-34: 124: 37.73
+	Hs
		838692 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB6B_HUMAN (54-214): 6.33e-34: 123: 39.13
+	Hs
		592641 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB6A_HUMAN (54-239): 1.98e-33: 122: 36.56
+	Mm
		722734 GDIB_MOUSE (1-444): 0: 695: 86.26		RAB6A_MOUSE (54-239): 1.98e-33: 122: 36.56