HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 406
+	Hs
		679160 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		211843 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		1304113 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Mm
		590496 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		RING2_MOUSE (8-406): 2.94e-100: 303: 54.25
+	Hs
		967951 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		718207 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		679164 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		717703 HXA4_HUMAN (30-286): 1.55e-35: 132: 23.90		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		679129 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		PCGF5_HUMAN (31-147): 4.96e-38: 139: 23.33
+	Hs
		590551 PO3F3_HUMAN (6-286): 8.47e-31: 123: 17.08		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		595583 HXA5_HUMAN (53-276): 6.78e-30: 116: 23.21		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		585071 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		RO52_HUMAN (33-392): 4.67e-43: 158: 13.14
+	Hs
		718428 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		PCGF2_HUMAN (31-377): 1.44e-41: 151: 14.37
+	Hs
		1311543 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		213349 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		PCGF5_HUMAN (31-147): 4.96e-38: 139: 23.33
+	Hs
		967957 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		211952 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		211899 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		PCGF5_HUMAN (31-147): 4.96e-38: 139: 23.33
+	Hs
		882136 GSC_HUMAN (58-285): 5.34e-30: 116: 20.61		PCGF5_HUMAN (31-147): 4.96e-38: 139: 23.33