HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 197
+	Hs
		679098 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		679096 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		679097 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		213323 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		213321 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		211840 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		211837 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		213322 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		980644 BARH1_HUMAN (19-322): 2.25e-32: 124: 23.36		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		211839 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		213326 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		447242 HXB5_HUMAN (53-273): 4.3e-39: 140: 22.22		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		211844 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		980675 EMX2_HUMAN (82-290): 1.39e-36: 133: 28.11		TLE2_HUMAN (2-149): 6.71e-80: 253: 71.62
+	Hs
		211838 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		TLE2_HUMAN (2-149): 6.71e-80: 253: 71.62
+	Hs
		980714 BARH1_HUMAN (19-322): 2.25e-32: 124: 23.36		TLE2_HUMAN (2-149): 6.71e-80: 253: 71.62
+	Dm
		558366 UBX_DROME (65-265): 4.1e-33: 128: 23.83		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Dm
		558365 GSC_DROME (4-269): 5.67e-30: 119: 20.30		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Ce
		137664 HM19_CAEEL (194-307): 1.11e-35: 130: 35.65		UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47
+	Ce
		137668 HM01_CAEEL (201-304): 3.43e-34: 123: 32.69		UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47