HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: AUTS2 (Q8WXX7)
Autism susceptibility gene 2 protein
Gene: AUTS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 1259
+	Hs
		679175 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		679174 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		213388 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		FBSL_HUMAN (79-931): 1.69e-39: 162: 35.03
+	Hs
		679137 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		KMT2C_HUMAN (430-1258): 3.63e-13: 77: 9.23
+	Hs
		213386 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		FBRS_HUMAN (563-885): 1.05e-30: 129: 41.54
+	Hs
		152596 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Hs
		679158 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		213358 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		KMT2C_HUMAN (430-1258): 3.63e-13: 77: 9.23
+	Hs
		152561 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Hs
		213372 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		CIC_HUMAN (124-1255): 2.4e-10: 67.4: 9.34
+	Hs
		211919 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		KMT2C_HUMAN (430-1258): 3.63e-13: 77: 9.23
+	Hs
		257599 HXA4_HUMAN (30-286): 1.55e-35: 132: 23.90		ANR17_HUMAN (242-849): 1.24e-11: 71.9: 10.62
+	Hs
		211855 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		NCOA6_HUMAN (63-1250): 4.76e-13: 76.3: 10.27
+	Hs
		257550 HXC4_HUMAN (109-293): 2.37e-34: 128: 25.39		ANR17_HUMAN (242-849): 1.24e-11: 71.9: 10.62
+	Hs
		257560 HXB6_HUMAN (58-279): 7.84e-35: 128: 23.42		ANR17_HUMAN (242-849): 1.24e-11: 71.9: 10.62
+	Hs
		152560 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		KMT2D_HUMAN (75-890): 1.52e-10: 68.4: 12.98
+	Mm
		590382 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		KMT2D_MOUSE (147-917): 3.93e-10: 66.9: 9.46
+	Mm
		590420 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		KMT2C_MOUSE (323-1230): 5.99e-10: 66.3: 9.64
+	Hs
		201848 HXA2_HUMAN (92-275): 6.32e-34: 130: 19.51		SYNJ1_HUMAN (497-932): 2.92e-09: 63.8: 11.26
+	Mm
		590489 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		ANR17_MOUSE (115-774): 8.6e-10: 65.7: 10.33