HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 2442
+	Hs
		656411 PIT1_HUMAN (8-267): 3.12e-37: 136: 13.64		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		1270832 PO2F3_HUMAN (20-326): 2.73e-35: 134: 16.40		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		568035 HXB6_HUMAN (58-279): 7.84e-35: 128: 23.42		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Rn
		94370 PIT1_RAT (8-267): 2.92e-36: 133: 13.26		F1M9G7_RAT (1-2442): 0: 1076: 95.46
+	Hs
		679102 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		999101 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		1334444 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		TRI33_HUMAN (694-1207): 3.25e-37: 156: 14.83
+	Hs
		170479 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		679131 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		967887 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		BRDT_HUMAN (1059-1195): 1.74e-34: 146: 25.55
+	Hs
		679182 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		679137 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		213352 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		1199200 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		213398 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		213358 TLX2_HUMAN (4-327): 2e-39: 142: 50.89		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		967910 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		201848 HXA2_HUMAN (92-275): 6.32e-34: 130: 19.51		SYNJ1_HUMAN (1984-2407): 1.04e-11: 73.3: 10.86
+	Hs
		967857 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09
+	Hs
		967993 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68