Protein: RFA2
Replication factor A protein 2 (RF-A protein 2) (DNA-binding protein BUF1) (Replication protein A 36 kDa subunit)

Gene: RFA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 83
UniProt ID: P26754

Gene Ontology (top 5):
GO:0000722 - telomere maintenance via recombination
GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0000794 - condensed nuclear chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

647711

RFA1
Replication factor A protein 1

17

9

Small-scale

0.986

High

688722

RFA3
Replication factor A protein 3

10

0

Small-scale

0.924

High

688741

ATR
Serine/threonine-protein kinase MEC1

9

10

Small-scale

0.755

High

448434

RAD52
DNA repair and recombination protein RAD52

7

3

Small-scale

0.746

High

688743

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

3

3

Small-scale

0.656

High

688747

RT105
Regulator of Ty1 transposition protein 105

3

0

Small-scale

0.656

High

675274

DMC1
Meiotic recombination protein DMC1

2

5

Small-scale

0.629

High

688721

RFA2
Replication factor A protein 2

1

3

Small-scale

0.621

High

380993

H2B1
Histone H2B.1

3

3

Small-scale

0.603

High

688761

SAE3
Pachytene arrest protein SAE3

2

0

Small-scale

0.603

High

419371

H2A1
Histone H2A.1

2

4

Small-scale

0.595

High

688726

MCM4
DNA replication licensing factor MCM4

2

5

Small-scale

0.584

High

688766

LCD1
DNA damage checkpoint protein LCD1

2

0

High-throughput

0.576

High

578953

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.571

High

381909

H4
Histone H4

2

2

Small-scale

0.570

High

688760

H3
Histone H3

2

3

Small-scale

0.570

High

688764

MSH6
DNA mismatch repair protein MSH6

2

5

High-throughput

0.567

High

688778

CMR1
DNA damage-binding protein CMR1

2

6

High-throughput

0.558

High

688731

IME2
Meiosis induction protein kinase IME2/SME1

2

6

Small-scale

0.550

High

688729

MEI5
Meiosis protein 5

1

0

Small-scale

0.537

High

688751

MPH1
ATP-dependent DNA helicase MPH1

2

13

Small-scale

0.533

High

533470

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

2

Small-scale

0.527

High

688774

SIZ2
E3 SUMO-protein ligase SIZ2

1

4

Small-scale

0.527

High

688767

KU80
ATP-dependent DNA helicase II subunit 2

1

5

Small-scale

0.515

High

688733

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.513

High

688723

RAD14
DNA repair protein RAD14

1

2

Small-scale

0.512

High

675310

RAD51
DNA repair protein RAD51

1

5

Small-scale

0.501

High

688740

ATM
Serine/threonine-protein kinase TEL1

1

9

Small-scale

0.501

High

688734

CDC13
Cell division control protein 13

1

0

Small-scale

0.493

High

688770

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.493

High

672219

CDC10
Cell division control protein 10

1

4

High-throughput

0.489

High

688728

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

6

High-throughput

0.489

High

419627

H2A2
Histone H2A.2

1

4

High-throughput

0.479

High

671480

RAD57
DNA repair protein RAD57

1

5

Small-scale

0.479

High

688727

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

688730

SPT16
FACT complex subunit SPT16

1

4

Small-scale

0.479

High

688738

BDF1
Bromodomain-containing factor 1

1

3

Small-scale

0.479

High

688758

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

5

Small-scale

0.479

High

688762

CTF4
DNA polymerase alpha-binding protein

1

8

Small-scale

0.479

High

688763

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

688765

CAF1B
Chromatin assembly factor 1 subunit B

1

5

Small-scale

0.479

High

688775

RAD59
DNA repair protein RAD59

1

3

Small-scale

0.479

High

460953

LTE1
Guanine nucleotide exchange factor LTE1

1

2

High-throughput

0.470

High

688753

RSC8
Chromatin structure-remodeling complex protein RSC8

1

1

High-throughput

0.470

High

688749

RT106
Histone chaperone RTT106

1

0

Small-scale

0.458

High

688776

PSY3
Platinum sensitivity protein 3

1

0

Small-scale

0.458

High

688754

DPB11
DNA replication regulator DPB11

1

2

Small-scale

0.457

High

688736

SGS1
ATP-dependent helicase SGS1

1

13

Small-scale

0.457

High

366956

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.457

High

673473

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

2

High-throughput

0.457

High

688737

MDJ1
DnaJ homolog 1, mitochondrial

1

1

High-throughput

0.457

High

688755

TCPQ
T-complex protein 1 subunit theta

1

7

High-throughput

0.457

High

688759

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

3

High-throughput

0.457

High

381429

H2B2
Histone H2B.2

1

3

High-throughput

0.437

High

392330

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.437

High

639543

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

1

High-throughput

0.437

High

656937

BUR1
Serine/threonine-protein kinase BUR1

1

9

Small-scale

0.437

High

688724

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

688725

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

688742

DPOA2
DNA polymerase alpha subunit B

1

1

High-throughput

0.437

High

688745

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

3

High-throughput

0.437

High

688757

PESC
Pescadillo homolog

1

1

High-throughput

0.437

High

688769

IMB1
Importin subunit beta-1

1

6

Small-scale

0.437

High

688772

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

688777

DBP10
ATP-dependent RNA helicase DBP10

1

12

High-throughput

0.437

High

523222

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

526062

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.407

High

544012

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

670400

SIS1
Protein SIS1

1

3

High-throughput

0.407

High

688732

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.407

High

688746

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.407

High

688748

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

688750

JEM1
DnaJ-like chaperone JEM1

1

3

High-throughput

0.407

High

653828

HSP12
12 kDa heat shock protein

2

0

High-throughput

0.307

High

688739

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.279

Low

688756

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.279

Low

688744

MNL1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.269

Low

688752

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

688768

BUR2
Protein BUR2

1

0

Small-scale

0.249

Low

688771

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

688773

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

688735

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025