Interactor 1: CDC48 (P25694)
Cell division control protein 48 (EC 3.6.4.6) (Cell division cycle protein 48) (Transitional endoplasmic reticulum ATPase homolog)
Gene: CDC48
Interactor 2: YME1 (P32795)
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1 (EC 3.4.24.-) (Protein OSD1) (Tat-binding homolog 11) (Yeast mitochondrial escape protein 1)
Gene: YME1
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 40359616 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA~AAA, AAA~AAA_lid_3, AAA~Peptidase_M41, AAA_lid_3~AAA_lid_3, AAA_lid_3~Peptidase_M41, AAA~CDC48_2, AAA_lid_3~CDC48_2, AAA~CDC48_N, AAA_lid_3~CDC48_N |
| Common GO terms | GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins GO:0016887 - ATP hydrolysis activity |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
