Protein: YTA12
Mitochondrial inner membrane m-AAA protease component YTA12 (EC 3.4.24.-) (EC 3.6.-.-) (Tat-binding homolog 12)

Gene: YTA12
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: P40341

Gene Ontology (top 5):
GO:0004176 - ATP-dependent peptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814941

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

9

14

Small-scale

0.965

High

823074

PHB1
Prohibitin-1

3

14

Small-scale

0.847

High

823076

PHB2
Prohibitin-2

2

14

High-throughput

0.789

High

679756

CDC48
Cell division control protein 48

1

6

High-throughput

0.618

High

752329

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.618

High

781392

MIC60
MICOS complex subunit MIC60

2

2

High-throughput

0.584

High

823075

TOM22
Mitochondrial import receptor subunit TOM22

2

2

High-throughput

0.584

High

803357

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

7

High-throughput

0.494

High

357773

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

1

High-throughput

0.479

High

357834

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

1

High-throughput

0.479

High

360794

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

High-throughput

0.479

High

360885

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

1

High-throughput

0.479

High

382923

RMAR
Small ribosomal subunit protein uS3m

1

2

High-throughput

0.479

High

399847

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

1

High-throughput

0.479

High

417112

VDAC1
Non-selective voltage-gated ion channel 1

1

2

High-throughput

0.479

High

432011

ATPF
ATP synthase subunit 4, mitochondrial

1

2

High-throughput

0.479

High

453162

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

7

High-throughput

0.479

High

453282

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

7

High-throughput

0.479

High

465340

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

2

High-throughput

0.479

High

470687

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

1

High-throughput

0.479

High

510543

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.479

High

579502

HSC82
ATP-dependent molecular chaperone HSC82

1

10

High-throughput

0.479

High

661800

TOM40
Mitochondrial import receptor subunit TOM40

1

2

High-throughput

0.479

High

736265

RM41
Large ribosomal subunit protein uL23m

1

1

High-throughput

0.479

High

746579

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

2

High-throughput

0.479

High

746855

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

3

High-throughput

0.479

High

781080

TCD2
tRNA threonylcarbamoyladenosine dehydratase 2

1

3

High-throughput

0.479

High

815683

OXA1
Mitochondrial inner membrane protein OXA1

1

3

High-throughput

0.479

High

818607

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

1

High-throughput

0.479

High

823072

PUP1
PUP1 protein homolog

1

1

High-throughput

0.479

High

823077

MCY1
Putative mitochondrial cysteine synthase

1

2

High-throughput

0.479

High

823078

RCF2
Respiratory supercomplex factor 2, mitochondrial

1

1

High-throughput

0.479

High

823079

ATP23
Mitochondrial inner membrane protease ATP23

1

1

High-throughput

0.479

High

823080

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

1

High-throughput

0.479

High

823081

VPS60
Vacuolar protein-sorting-associated protein 60

1

3

Small-scale

0.479

High

823083

ATG33
Autophagy-related protein 33

1

1

High-throughput

0.479

High

823084

YD157
Uncharacterized protein YDL157C, mitochondrial

1

1

Small-scale

0.479

High

734558

MSS51
Protein MSS51, mitochondrial

1

0

High-throughput

0.458

High

780569

PMU1
Probable phosphoglycerate mutase PMU1

1

0

High-throughput

0.458

High

392825

HSP82
ATP-dependent molecular chaperone HSP82

1

10

High-throughput

0.445

High

526843

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

545088

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

592288

VATB
V-type proton ATPase subunit B

1

6

High-throughput

0.445

High

676048

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

670783

SIS1
Protein SIS1

1

4

High-throughput

0.437

High

531766

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.407

High

554432

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

2

High-throughput

0.407

High

677426

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

738316

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.249

Low

823073

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

823082

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025