HitPredict

Interactor 1: AKT1 (P31750)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (AKT1 kinase) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha) (Thymoma viral proto-oncogene)
Gene: AKT1

Interactor 2: MTOR (Q9JLN9)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)
Gene: MTOR

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 17660512, 18566586
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001938 - positive regulation of endothelial cell proliferation
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 25 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 480
Mm

1 2549
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+ Rn
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Last updated: 15 Jul 2024