Protein: CAPZA
F-actin-capping protein subunit alpha

Gene: CAPZA, cpa
Organism: Drosophila melanogaster
Interactions: 69
UniProt ID: Q9W2N0

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0007015 - actin filament organization
GO:0007294 - germarium-derived oocyte fate determination
GO:0008290 - F-actin capping protein complex
GO:0010591 - regulation of lamellipodium assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

875151

CAPZB
F-actin-capping protein subunit beta

4

7

High-throughput

0.878

High

736434

ARP3
Actin-related protein 3

2

11

High-throughput

0.737

High

852921

ARP2
Actin-related protein 2

2

11

High-throughput

0.737

High

921009

ACT3
Actin-57B

2

9

High-throughput

0.659

High

1014465

ACT6
Actin, indirect flight muscle

1

9

High-throughput

0.575

High

1322019

Q8MYY7
RE44624p

1

3

High-throughput

0.575

High

52566

A1Z6Z9
Dilute class unconventional myosin, isoform A

2

6

High-throughput

0.571

High

357029

O97182
Actin-related protein 2/3 complex subunit

2

1

High-throughput

0.571

High

52747

A1Z734
Leucine-rich repeat, isoform B

1

9

High-throughput

0.553

High

95032

E1JGZ8
Leucine-rich repeat, isoform C

1

8

High-throughput

0.553

High

1478033

EFHD2
EF-hand domain-containing protein D2 homolog

2

4

High-throughput

0.521

High

1481747

Q9VMH2
Actin-related protein 2/3 complex subunit 4

2

1

High-throughput

0.521

High

1484113

Q9VQD8
Actin-related protein 2/3 complex subunit 5

2

2

High-throughput

0.521

High

1488335

Q9VXN3
LD07988p

2

6

High-throughput

0.521

High

534516

ACT1
Actin-5C

1

9

High-throughput

0.514

High

1173721

SEM1A
Semaphorin-1A

1

1

High-throughput

0.489

High

119418

M9NFI9
Neurabin-1

1

5

High-throughput

0.484

High

1478767

Q9VJW5
E3 ubiquitin-protein ligase NRDP1

1

3

High-throughput

0.464

High

1467295

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

Small-scale

0.458

High

69120

A8JRH3
FI20012p1

1

2

High-throughput

0.445

High

561616

SPTCA
Spectrin alpha chain

1

11

High-throughput

0.445

High

823818

SQH
Myosin regulatory light chain sqh

1

4

High-throughput

0.445

High

1028096

SPTCB
Spectrin beta chain

1

11

High-throughput

0.445

High

1038069

HTS
Protein hu-li tai shao

1

2

High-throughput

0.445

High

1171761

FLII
Protein flightless-1

1

4

High-throughput

0.445

High

1262357

Q7JVY0
Coronin

1

3

High-throughput

0.445

High

1473540

Q9VF28
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.445

High

68739

A8JQV1
Uncharacterized protein, isoform C

1

3

High-throughput

0.437

High

654434

DDX6
ATP-dependent RNA helicase me31b

1

1

High-throughput

0.437

High

1173833

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

1

High-throughput

0.437

High

1265183

DCTN2
Dynactin subunit 2

1

2

High-throughput

0.437

High

1303765

AKT1
RAC serine/threonine-protein kinase

1

3

High-throughput

0.437

High

1375041

Q94533
Ribosomal protein S6 kinase

1

3

High-throughput

0.437

High

1473230

Q9VEV3
Tetratricopeptide repeat protein 1

1

1

High-throughput

0.437

High

1477657

ARPC2
Actin-related protein 2/3 complex subunit 2

1

1

High-throughput

0.437

High

1482602

RHEB
GTP-binding protein Rheb homolog

1

1

High-throughput

0.437

High

1488662

Q9VYB1
Kinetochore protein NDC80

1

9

Small-scale

0.437

High

1489194

DOS
Protein daughter of sevenless

1

7

High-throughput

0.437

High

235260

HTH
Homeobox protein homothorax

1

0

High-throughput

0.426

High

1489198

Q9W016
Supervillin, isoform K

1

0

High-throughput

0.426

High

614498

SGG
Protein kinase shaggy

1

1

High-throughput

0.407

High

1069564

Q0E8S4
Semaphorin-1A

1

1

High-throughput

0.407

High

1181191

Q32KE1
RE04201p

1

1

High-throughput

0.407

High

1196468

Q4V467
IP10845p

1

3

High-throughput

0.407

High

1202461

Q59E59
Zipper, isoform D

1

4

High-throughput

0.407

High

1303671

Q8IN95
Nuclear migration protein nudC

1

1

High-throughput

0.407

High

1304251

Q8INW7
FI11475p

1

4

High-throughput

0.407

High

1485518

Q9VSD6
D-Importin 7/RanBP7

1

1

High-throughput

0.407

High

1171944

Q24090
GH08712p

1

0

High-throughput

0.282

High

1196760

Q4V6W7
IP01184p

1

0

High-throughput

0.265

Low

1468115

Q9VAL8
Uncharacterized protein, isoform C

1

0

High-throughput

0.265

Low

1470918

ADRL
Adiponectin receptor protein

1

0

High-throughput

0.265

Low

1471754

Q9VDM7
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.265

Low

1488543

Q9VY14
Uncharacterized protein

1

0

High-throughput

0.265

Low

122185

M9PHX2
Visgun, isoform E

1

0

High-throughput

0.253

Low

633053

GLNA2
Glutamine synthetase 2 cytoplasmic

1

0

High-throughput

0.253

Low

669644

OSKA
Maternal effect protein oskar

1

0

Small-scale

0.249

Low

1172717

SIMA
Protein similar

1

0

High-throughput

0.249

Low

357448

O97471
Microsomal glutathione S-transferase 1

1

0

High-throughput

0.232

Low

1175514

NETB
Netrin-B

1

0

High-throughput

0.232

Low

1302952

Q8IHH3
AT01055p

1

0

High-throughput

0.232

Low

1305214

MCU
Calcium uniporter protein, mitochondrial

1

0

High-throughput

0.232

Low

1377209

GILT1
GILT-like protein 1

1

0

High-throughput

0.232

Low

1467697

Q9VAC1
GM14349p

1

0

High-throughput

0.232

Low

1472161

INO80
Chromatin-remodeling ATPase INO80

1

0

High-throughput

0.232

Low

1480665

Q9VLB7
Rab GDP dissociation inhibitor

1

0

High-throughput

0.232

Low

1484817

Q9VRD4
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1489481

Q9W0U6
Sulfatase-modifying factor enzyme-like domain-containing protein

1

0

High-throughput

0.232

Low

1489714

Q9W255
GH05812p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025