HitPredict

Interactor 1: AKT2 (P31751)
RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC protein kinase beta) (RAC-PK-beta)
Gene: AKT2

Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 14504284, 32296183, 17535800
Identification Methods pull down, two hybrid, enzymatic study, in-gel kinase assay, protein kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~SH3_1, PH~SH3_9
Common GO terms GO:0005829 - cytosol
GO:0046872 - metal ion binding
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 481
Hs

1 888
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024