HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.734

Property	Details
Experiments	27432908, 22948661, 33961781, 36931259, 24255178, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1187
+	Hs
		909595 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		927076 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		909614 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN21_HUMAN (1-1187): 0: 817: 52.29
+	Hs
		683381 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN21_HUMAN (1-1187): 0: 817: 52.29
+	Hs
		910025 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L1_HUMAN (5-713): 7.06e-142: 453: 17.33
+	Hs
		683710 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L1_HUMAN (5-713): 7.06e-142: 453: 17.33
+	Hs
		577010 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTPRA_HUMAN (428-1181): 5.96e-139: 442: 18.42
+	Hs
		910185 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L3_HUMAN (13-857): 2.64e-133: 435: 16.82
+	Hs
		683836 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L3_HUMAN (13-857): 2.64e-133: 435: 16.82
+	Hs
		663970 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN4_HUMAN (598-1183): 2.04e-126: 413: 23.38
+	Hs
		663962 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN4_HUMAN (598-1183): 2.04e-126: 413: 23.38
+	Hs
		663973 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN4_HUMAN (598-1183): 2.04e-126: 413: 23.38
+	Hs
		683735 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L5_HUMAN (17-319): 2.76e-117: 382: 27.33
+	Hs
		547003 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		640229 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN3_HUMAN (3-879): 1.01e-90: 315: 15.76
+	Hs
		640216 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN3_HUMAN (3-879): 1.01e-90: 315: 15.76
+	Hs
		640230 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN3_HUMAN (3-879): 1.01e-90: 315: 15.76
+	Hs
		909498 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		683305 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		926984 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36