HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: DOCK4 (Q8N1I0)
Dedicator of cytokinesis protein 4
Gene: DOCK4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15324660
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1966
+	Hs
		909993 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DOCK9_HUMAN (915-1594): 0: 629: 16.22
+	Hs
		683685 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DOCK9_HUMAN (915-1594): 0: 629: 16.22
+	Hs
		927490 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DOCK9_HUMAN (915-1594): 0: 629: 16.22
+	Hs
		909638 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DOC11_HUMAN (922-1631): 0: 611: 16.24
+	Hs
		683403 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DOC11_HUMAN (922-1631): 0: 611: 16.24
+	Hs
		927120 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DOC11_HUMAN (922-1631): 0: 611: 16.24
+	Hs
		63199 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		A6NIW2_HUMAN (922-1631): 0: 606: 16.28
+	Mm
		56981 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		A2A9M5_MOUSE (699-1065): 7.41e-61: 234: 12.01
+	Hs
		909920 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DOCK7_HUMAN (699-1065): 1.41e-60: 233: 11.77
+	Hs
		683630 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DOCK7_HUMAN (699-1065): 1.41e-60: 233: 11.77
+	Mm
		56982 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		A2A9M5_MOUSE (699-1065): 7.41e-61: 234: 12.01
+	Hs
		927415 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DOCK7_HUMAN (699-1065): 1.41e-60: 233: 11.77
+	Mm
		910297 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DOCK8_MOUSE (699-940): 2.6e-51: 203: 12.96
+	Hs
		297821 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		K0754_HUMAN (1413-1966): 5.1e-27: 123: 10.58
+	Hs
		297815 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		K0754_HUMAN (1413-1966): 5.1e-27: 123: 10.58
+	Hs
		297824 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (1413-1966): 5.1e-27: 123: 10.58
+	Hs
		909712 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		OTOG_HUMAN (1489-1886): 5.63e-17: 90.2: 10.05
+	Hs
		683472 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		OTOG_HUMAN (1489-1886): 5.63e-17: 90.2: 10.05
+	Hs
		927196 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		OTOG_HUMAN (1489-1886): 5.63e-17: 90.2: 10.05
+	Hs
		927549 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TENS1_HUMAN (1564-1964): 3.26e-11: 71.3: 17.78