HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SIN1 (Q9BPZ7)
Target of rapamycin complex 2 subunit MAPKAP1 (TORC2 subunit MAPKAP1) (Mitogen-activated protein kinase 2-associated protein 1) (Stress-activated map kinase-interacting protein 1) (SAPK-interacting protein 1) (mSIN1)
Gene: MAPKAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 522
+	Hs
		909962 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SIN1_HUMAN (1-522): 0: 894: 100.00
+	Hs
		927461 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SIN1_HUMAN (1-522): 0: 894: 100.00
+	Hs
		647226 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		SIN1_HUMAN (1-522): 0: 894: 100.00
+	Hs
		905046 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		SIN1_HUMAN (1-522): 0: 894: 100.00
+	Hs
		982433 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		SIN1_HUMAN (1-522): 0: 894: 100.00
+	Hs
		684295 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		SIN1_HUMAN (1-522): 0: 894: 100.00
+	Dm
		955016 1433E_DROME (3-245): 4.63e-144: 405: 64.90		SIN1_DROME (1-508): 0: 522: 25.04