HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: MLXIP (Q9HAP2)
MLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA)
Gene: MLXIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.50	0.566

Property	Details
Experiments	12446771, 36931259
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 919
+	Hs
		910039 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MLXIP_HUMAN (1-919): 1.25e-172: 527: 100.00
+	Hs
		927544 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MLXIP_HUMAN (1-919): 1.25e-172: 527: 100.00
+	Hs
		927559 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MLXPL_HUMAN (61-910): 2.92e-92: 312: 35.38
+	Hs
		910128 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MLX_HUMAN (588-888): 1.47e-36: 141: 23.47
+	Hs
		683792 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MLX_HUMAN (588-888): 1.47e-36: 141: 23.47
+	Hs
		927628 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MLX_HUMAN (588-888): 1.47e-36: 141: 23.47
+	Hs
		846916 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SMCA4_HUMAN (317-829): 2.82e-24: 112: 10.08
+	Hs
		297821 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		K0754_HUMAN (175-508): 1.33e-15: 84.4: 10.47
+	Hs
		297815 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		K0754_HUMAN (175-508): 1.33e-15: 84.4: 10.47
+	Hs
		909712 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		OTOG_HUMAN (237-592): 3.46e-15: 82.8: 11.91
+	Hs
		683472 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		OTOG_HUMAN (237-592): 3.46e-15: 82.8: 11.91
+	Hs
		297824 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (175-508): 1.33e-15: 84.4: 10.47
+	Hs
		927196 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		OTOG_HUMAN (237-592): 3.46e-15: 82.8: 11.91
+	Hs
		257595 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ANR17_HUMAN (341-729): 1.68e-09: 64.3: 12.56
+	Hs
		257572 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		ANR17_HUMAN (341-729): 1.68e-09: 64.3: 12.56
+	Hs
		909755 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PHLB1_HUMAN (280-812): 9.56e-09: 61.6: 12.64
+	Hs
		683504 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PHLB1_HUMAN (280-812): 9.56e-09: 61.6: 12.64
+	Hs
		257597 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ANR17_HUMAN (341-729): 1.68e-09: 64.3: 12.56
+	Hs
		927241 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PHLB1_HUMAN (280-812): 9.56e-09: 61.6: 12.64
+	Hs
		257566 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		ANR17_HUMAN (341-729): 1.68e-09: 64.3: 12.56