HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: TRAK1 (Q9UPV9)
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
Gene: TRAK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006605 - protein targeting GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 953
+	Hs
		910164 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TRAK1_HUMAN (1-953): 0: 646: 100.00
+	Rn
		869343 1433E_RAT (3-243): 4.39e-144: 405: 65.43		HAP1_RAT (91-524): 3.53e-28: 123: 23.20
+	Rn
		869346 1433Z_RAT (3-244): 3.14e-142: 399: 88.02		HAP1_RAT (91-524): 3.53e-28: 123: 23.20
+	Hs
		909658 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MRCKA_HUMAN (4-678): 5.5e-23: 108: 10.13
+	Hs
		683425 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MRCKA_HUMAN (4-678): 5.5e-23: 108: 10.13
+	Hs
		927145 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MRCKA_HUMAN (4-678): 5.5e-23: 108: 10.13
+	Hs
		551660 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DESP_HUMAN (38-579): 1.38e-20: 100: 10.28
+	Hs
		927164 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MRCKG_HUMAN (23-365): 5.69e-20: 98.5: 15.43
+	Hs
		725130 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH10_HUMAN (9-491): 2.9e-17: 89.5: 10.79
+	Hs
		728460 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH11_HUMAN (196-629): 6.39e-17: 88.3: 11.38
+	Mm
		926855 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH9_MOUSE (1-468): 5.26e-18: 92.2: 11.16
+	Hs
		724761 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH9_HUMAN (195-661): 7.37e-17: 88.3: 10.53
+	Hs
		728466 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH11_HUMAN (196-629): 6.39e-17: 88.3: 11.38
+	Hs
		253248 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KI21B_HUMAN (22-544): 4.05e-14: 79.1: 8.35
+	Hs
		522602 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH7_HUMAN (6-392): 7.1e-15: 81.8: 10.23
+	Hs
		927643 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH2_HUMAN (262-723): 2.67e-14: 79.9: 9.83
+	Mm
		910349 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		KI21B_MOUSE (34-515): 4.41e-11: 69.5: 8.52
+	Mm
		926804 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH10_MOUSE (23-430): 8.73e-13: 75: 10.19
+	Mm
		890551 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		LIPA3_MOUSE (39-318): 2.52e-11: 69.9: 14.29
+	Mm
		926868 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYO5A_MOUSE (37-478): 4.71e-09: 62.7: 12.15