HitPredict

Interactor 1: UTP7 (P40055)
U3 small nucleolar RNA-associated protein 7 (U3 snoRNA-associated protein 7) (U three protein 7)
Gene: UTP7

Interactor 2: UTP15 (Q04305)
U3 small nucleolar RNA-associated protein 15 (U3 snoRNA-associated protein 15) (U three protein 15) (U3 protein 15 required for transcription) (t-UTP15)
Gene: UTP15

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.900

Property	Details
Experiments	11805826, 37968396, 12150911, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 554 Sc			1 513
+	Hs
		1281473 PRP19_HUMAN (50-386): 8.95e-83: 268: 17.66		FBXW7_HUMAN (5-371): 7.23e-77: 257: 14.47
+	Hs
		1309163 TBL1R_HUMAN (171-463): 1.3e-53: 191: 10.76		TBL1Y_HUMAN (9-286): 2.17e-62: 214: 13.33
+	Hs
		903418 WDR5_HUMAN (167-386): 4.43e-33: 131: 14.41		FBXW7_HUMAN (5-371): 7.23e-77: 257: 14.47
+	Hs
		793026 KTNB1_HUMAN (201-407): 1.84e-64: 224: 16.98		LIS1_HUMAN (244-453): 1.1e-35: 139: 9.05
+	Hs
		1288388 PRP19_HUMAN (50-386): 8.95e-83: 268: 17.66		SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44
+	Hs
		921751 GBB2_HUMAN (55-260): 1.52e-40: 151: 12.62		NLE1_HUMAN (1-237): 7.9e-54: 190: 14.09
+	Hs
		903605 PRP19_HUMAN (50-386): 8.95e-83: 268: 17.66		WDR5_HUMAN (333-420): 2.73e-12: 69.9: 10.23
+	Hs
		903551 WDR5_HUMAN (167-386): 4.43e-33: 131: 14.41		NLE1_HUMAN (1-237): 7.9e-54: 190: 14.09
+	Hs
		245633 TBL1R_HUMAN (171-463): 1.3e-53: 191: 10.76		TBL1X_HUMAN (201-428): 8.23e-31: 128: 10.79
+	Hs
		245630 TBL1Y_HUMAN (188-465): 1.91e-52: 188: 11.92		TBL1X_HUMAN (201-428): 8.23e-31: 128: 10.79
+	Sp
		999838 TUP11_SCHPO (215-464): 2.6e-47: 176: 11.81		TUP11_SCHPO (282-428): 5.04e-20: 95.3: 13.55
+	Hs
		792949 WDR5_HUMAN (167-386): 4.43e-33: 131: 14.41		LIS1_HUMAN (244-453): 1.1e-35: 139: 9.05
+	Sp
		999842 TUP12_SCHPO (9-263): 3.26e-43: 164: 9.89		TUP11_SCHPO (282-428): 5.04e-20: 95.3: 13.55
+	Hs
		1240442 POC1B_HUMAN (219-464): 3.33e-51: 184: 8.91		POC1A_HUMAN (333-416): 1.55e-12: 71: 8.33
+	Hs
		903428 WDR5_HUMAN (167-386): 4.43e-33: 131: 14.41		SNR40_HUMAN (2-105): 9.6e-19: 89.5: 10.44
+	Hs
		903077 WDR5_HUMAN (167-386): 4.43e-33: 131: 14.41		WDR5_HUMAN (333-420): 2.73e-12: 69.9: 10.23
+	Hs
		903349 WDR5_HUMAN (167-386): 4.43e-33: 131: 14.41		WDR5B_HUMAN (333-420): 3.67e-12: 69.5: 11.36
+	Hs
		903174 WDR5_HUMAN (167-386): 4.43e-33: 131: 14.41		TBL3_HUMAN (262-421): 2.27e-11: 68.3: 10.37