HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RPGP1 (P47736)
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)
Gene: RAP1GAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 663
+	Hs
		812874 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGP1_HUMAN (1-663): 0: 837: 100.00
+	Hs
		812876 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RPGP1_HUMAN (1-663): 0: 837: 100.00
+	Hs
		909669 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RPGP2_HUMAN (1-645): 0: 778: 52.79
+	Hs
		927156 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RPGP2_HUMAN (1-645): 0: 778: 52.79
+	Hs
		684372 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SI1L2_HUMAN (54-401): 2.19e-144: 461: 35.33
+	Hs
		196406 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SI1L1_HUMAN (48-431): 3.91e-139: 448: 33.01
+	Hs
		230209 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SI1L3_HUMAN (48-400): 2.5e-136: 440: 35.85
+	Hs
		910116 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SI1L2_HUMAN (54-401): 2.19e-144: 461: 35.33
+	Hs
		196427 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SI1L1_HUMAN (48-431): 3.91e-139: 448: 33.01
+	Hs
		230231 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SI1L3_HUMAN (48-400): 2.5e-136: 440: 35.85
+	Hs
		196429 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SI1L1_HUMAN (48-431): 3.91e-139: 448: 33.01
+	Hs
		230235 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SI1L3_HUMAN (48-400): 2.5e-136: 440: 35.85
+	Hs
		683908 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		TSC2_HUMAN (131-476): 3.29e-103: 347: 19.42
+	Hs
		835035 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TSC2_HUMAN (131-476): 3.29e-103: 347: 19.42
+	Hs
		835039 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		TSC2_HUMAN (131-476): 3.29e-103: 347: 19.42
+	Hs
		684116 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		RGPA1_HUMAN (176-420): 6.51e-78: 273: 24.08
+	Dm
		114606 1433E_DROME (2-247): 2.8e-144: 405: 58.07		M9PD17_DROME (130-467): 1.62e-80: 281: 18.53
+	Dm
		955043 1433E_DROME (2-247): 2.8e-144: 405: 58.07		Q9VW83_DROME (130-467): 1.62e-80: 281: 18.53
+	Hs
		909678 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RGPA1_HUMAN (176-420): 6.51e-78: 273: 24.08
+	Mm
		926787 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		Q3TQ10_MOUSE (225-477): 6.07e-83: 263: 17.51