HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: CLK3 (P49761)
Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3)
Gene: CLK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 638
+	Hs
		834015 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CLK3_HUMAN (1-638): 0: 542: 100.00
+	Hs
		834018 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CLK3_HUMAN (1-638): 0: 542: 100.00
+	Hs
		683964 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK3_HUMAN (301-632): 2.49e-129: 384: 23.89
+	Hs
		684022 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20
+	Hs
		625306 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26
+	Hs
		684246 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYRK2_HUMAN (93-633): 2.19e-117: 364: 23.45
+	Hs
		684347 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYRK4_HUMAN (199-637): 3.87e-116: 358: 25.74
+	Hs
		414774 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK1_HUMAN (301-624): 5.68e-119: 357: 24.70
+	Hs
		909447 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK3_HUMAN (301-632): 2.49e-129: 384: 23.89
+	Hs
		909539 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20
+	Mm
		910255 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DYR1A_MOUSE (181-637): 2.9e-122: 382: 26.45
+	Hs
		625334 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26
+	Hs
		684420 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYR1B_HUMAN (210-633): 7.87e-110: 345: 26.85
+	Hs
		909877 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYRK2_HUMAN (93-633): 2.19e-117: 364: 23.45
+	Hs
		910066 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYRK4_HUMAN (199-637): 3.87e-116: 358: 25.74
+	Hs
		927021 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DYR1A_HUMAN (181-637): 4.69e-123: 384: 26.20
+	At
		847169 14332_ARATH (3-248): 2.23e-144: 405: 58.47		AFC1_ARATH (276-627): 6.05e-118: 361: 40.60
+	Hs
		910197 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYR1B_HUMAN (210-633): 7.87e-110: 345: 26.85
+	Hs
		625130 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CDK2_HUMAN (301-631): 4.28e-138: 406: 24.26
+	Hs
		646727 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		CLK2_HUMAN (149-638): 5.31e-135: 406: 58.52