Protein: TF2H1
General transcription factor IIH subunit 1 (Basic transcription factor 2 62 kDa subunit) (BTF2 p62) (General transcription factor IIH polypeptide 1) (TFIIH basal transcription factor complex p62 subunit)

Gene: TF2H1, GTF2H1
Organism: Homo sapiens
Interactions: 88
UniProt ID: P32780

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000439 - transcription factor TFIIH core complex
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0005675 - transcription factor TFIIH holo complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

584559

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

15

2

Small-scale

0.980

High

697742

TF2H2
General transcription factor IIH subunit 2

10

2

Small-scale

0.972

High

386188

P53
Cellular tumor antigen p53

5

1

Small-scale

0.935

High

663998

T2EA
General transcription factor IIE subunit 1

5

2

Small-scale

0.933

High

574130

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

5

2

Small-scale

0.928

High

697750

T2H2L
General transcription factor IIH subunit 2-like protein

4

2

Small-scale

0.895

High

697726

CDK7
Cyclin-dependent kinase 7

13

2

Small-scale

0.758

High

697743

TF2H3
General transcription factor IIH subunit 3

7

1

Small-scale

0.753

High

697740

KLF1
Krueppel-like factor 1

1

0

Small-scale

0.709

High

697736

XPC
DNA repair protein complementing XP-C cells

5

3

Small-scale

0.709

High

697727

CCNH
Cyclin-H

5

1

Small-scale

0.691

High

659903

ERCC5
DNA excision repair protein ERCC-5

4

1

Small-scale

0.689

High

697753

TF2H5
General transcription factor IIH subunit 5

5

0

Small-scale

0.689

High

697760

TF2H4
General transcription factor IIH subunit 4

4

2

Small-scale

0.689

High

624785

RPB1
DNA-directed RNA polymerase II subunit RPB1

5

0

Small-scale

0.674

High

697728

MAT1
CDK-activating kinase assembly factor MAT1

3

2

Small-scale

0.670

High

369075

ESR1
Estrogen receptor

3

4

Small-scale

0.650

High

612962

TCEA1
Transcription elongation factor A protein 1

3

0

Small-scale

0.619

High

697735

E2F1
Transcription factor E2F1

2

0

Small-scale

0.603

High

697719

T2FA
General transcription factor IIF subunit 1

2

1

Small-scale

0.584

High

697746

BRD3
Bromodomain-containing protein 3

2

2

High-throughput

0.584

High

697744

FHL2
Four and a half LIM domains protein 2

2

0

High-throughput

0.580

High

697764

EAF1
ELL-associated factor 1

2

0

High-throughput

0.580

High

346058

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

552049

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.559

High

650479

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

Small-scale

0.559

High

697749

UVSSA
UV-stimulated scaffold protein A

2

0

Small-scale

0.559

High

583403

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

Small-scale

0.536

High

617448

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.536

High

697738

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

659692

RXRB
Retinoic acid receptor RXR-beta

1

3

Small-scale

0.527

High

198794

HXC11
Homeobox protein Hox-C11

1

0

High-throughput

0.518

High

697731

BRPF1
Peregrin

1

0

High-throughput

0.518

High

697758

JDP2
Jun dimerization protein 2

1

0

High-throughput

0.518

High

125849

CDC7
Cell division cycle 7-related protein kinase

1

0

High-throughput

0.513

High

697721

CETN2
Centrin-2

1

0

High-throughput

0.513

High

697771

PRD11
PR domain-containing protein 11

1

0

High-throughput

0.513

High

697774

NUDC
Nuclear migration protein nudC

1

0

High-throughput

0.513

High

174662

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

475397

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

Small-scale

0.501

High

697722

HNF4A
Hepatocyte nuclear factor 4-alpha

1

3

Small-scale

0.501

High

697729

RD23A
UV excision repair protein RAD23 homolog A

1

2

Small-scale

0.501

High

263535

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.493

High

697747

TOM34
Mitochondrial import receptor subunit TOM34

1

1

High-throughput

0.489

High

487174

ANDR
Androgen receptor

1

4

Small-scale

0.479

High

612464

XPA
DNA repair protein complementing XP-A cells

1

1

Small-scale

0.479

High

631357

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.479

High

697724

CLK2
Dual specificity protein kinase CLK2

1

3

High-throughput

0.479

High

697725

CLK3
Dual specificity protein kinase CLK3

1

3

High-throughput

0.479

High

697730

RD23B
UV excision repair protein RAD23 homolog B

1

3

Small-scale

0.479

High

697759

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

131386

IMA4
Importin subunit alpha-4

1

0

High-throughput

0.460

High

697745

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.460

High

434564

ERCC1
DNA excision repair protein ERCC-1

1

0

Small-scale

0.458

High

569277

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

697720

PRS7
26S proteasome regulatory subunit 7

1

0

Small-scale

0.458

High

697732

ANM2
Protein arginine N-methyltransferase 2

1

0

High-throughput

0.458

High

697739

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

697741

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.458

High

697754

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

697761

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.458

High

697762

XPF
DNA repair endonuclease XPF

1

0

Small-scale

0.458

High

697763

FUBP1
Far upstream element-binding protein 1

1

0

Small-scale

0.458

High

697766

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

Small-scale

0.458

High

697772

ANLN
Anillin

1

0

High-throughput

0.458

High

697773

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

697756

USBP1
Harmonin-binding protein USHBP1

1

1

High-throughput

0.439

High

123863

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.438

High

697723

CLK1
Dual specificity protein kinase CLK1

1

3

High-throughput

0.437

High

697737

FGL1
Fibrinogen-like protein 1

3

0

High-throughput

0.347

High

697767

LZTS2
Leucine zipper putative tumor suppressor 2

2

0

High-throughput

0.328

High

697751

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

697770

TRXR2
Thioredoxin reductase 2, mitochondrial

1

0

Small-scale

0.299

High

697748

OBF1
POU domain class 2-associating factor 1

1

0

High-throughput

0.282

High

697757

ZSCA1
Zinc finger and SCAN domain-containing protein 1

1

0

High-throughput

0.282

High

697769

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

0

High-throughput

0.282

High

672639

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

674628

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.279

Low

697733

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.279

Low

697755

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.279

Low

527315

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

697775

SHLB1
Endophilin-B1

1

0

High-throughput

0.268

Low

521478

ACTN1
Alpha-actinin-1

1

0

High-throughput

0.251

Low

697734

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.251

Low

697768

TARA
TRIO and F-actin-binding protein

1

0

High-throughput

0.251

Low

697752

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

697776

RNF11
RING finger protein 11

1

0

Small-scale

0.249

Low

697765

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024