Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 24510904, 31046837, 28202711, unassigned1853
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, protein array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0070062 - extracellular exosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 248
Hs

1 2527
+ Hs
+ Mm
+ Mm
+ At
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Zm
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024