HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1121
+	Hs
		909680 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		684333 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		910040 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		125183 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		684286 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CYH2_HUMAN (105-300): 1.31e-44: 168: 21.50
+	Hs
		876345 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		125318 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Mm
		910223 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		CYH2_MOUSE (105-300): 1.44e-44: 168: 21.50
+	Mm
		926832 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		CNKR2_MOUSE (119-516): 8.05e-46: 181: 17.87
+	Hs
		910027 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		684276 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Mm
		93259 1433S_MOUSE (1-248): 4.84e-154: 429: 97.58		E9PXB7_MOUSE (59-486): 2.89e-28: 125: 13.02
+	Mm
		93264 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		E9PXB7_MOUSE (59-486): 2.89e-28: 125: 13.02
+	Mm
		910302 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		NED4L_MOUSE (59-486): 8.19e-27: 120: 12.02
+	Hs
		684266 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		909930 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		683894 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Rn
		910358 1433E_RAT (2-246): 4.41e-146: 410: 60.41		NEDD4_RAT (11-97): 3.59e-19: 95.8: 25.93
+	Hs
		808077 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Mm
		808343 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		NEDD4_MOUSE (14-322): 7.06e-14: 78.5: 11.64