HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	36931259, 37120454, 15778465
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0030307 - positive regulation of cell growth
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 1708
+	Hs
		909697 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		927182 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		647014 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		683461 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		904731 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		982159 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Dm
		955044 1433E_DROME (2-247): 2.8e-144: 405: 58.07		Q9VWJ6_DROME (1566-1694): 2.64e-11: 71.3: 34.62
+	Dm
		664664 1433Z_DROME (1-245): 4.71e-99: 290: 66.12		Q9VWJ6_DROME (1566-1694): 2.64e-11: 71.3: 34.62