Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: BAD (Q92934)
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)
Gene: BAD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 20005908, 36931259, 11697890, 16189514, 31980649, 33961781, 21988832, unassigned2173, 20179209
Identification Methods affinity chromatography technology, pull down, two hybrid, two hybrid array, anti tag coimmunoprecipitation, coimmunoprecipitation, cross-linking study, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005829 - cytosol
GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage
GO:0019901 - protein kinase binding
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 248
Hs

1 168
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024