HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: KKCC2 (Q96RR4)
Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)
Gene: CAMKK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 588
+	Hs
		681682 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		AKT1_HUMAN (83-515): 8.15e-132: 395: 22.27
+	Hs
		683974 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KPCE_HUMAN (64-492): 8.86e-126: 388: 21.04
+	Hs
		684209 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		KKCC1_HUMAN (61-536): 2.29e-126: 382: 61.59
+	Hs
		681770 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AKT1_HUMAN (83-515): 8.15e-132: 395: 22.27
+	At
		1280891 14337_ARATH (2-247): 4.35e-147: 413: 58.07		CIPKC_ARATH (145-562): 4.42e-128: 386: 23.15
+	Hs
		909458 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KPCE_HUMAN (64-492): 8.86e-126: 388: 21.04
+	Hs
		909813 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		KKCC1_HUMAN (61-536): 2.29e-126: 382: 61.59
+	At
		788672 14333_ARATH (3-247): 2.63e-144: 405: 58.30		CIPKC_ARATH (145-562): 4.42e-128: 386: 23.15
+	Rn
		910354 1433E_RAT (2-246): 4.41e-146: 410: 60.41		KKCC1_RAT (71-536): 7.59e-126: 381: 63.11
+	At
		965360 14332_ARATH (3-248): 2.23e-144: 405: 58.47		CIPKC_ARATH (145-562): 4.42e-128: 386: 23.15
+	Hs
		681776 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		AKT1_HUMAN (83-515): 8.15e-132: 395: 22.27
+	Hs
		926942 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		KPCE_HUMAN (64-492): 8.86e-126: 388: 21.04
+	Hs
		646812 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KPCE_HUMAN (64-492): 8.86e-126: 388: 21.04
+	Hs
		647107 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		KKCC1_HUMAN (61-536): 2.29e-126: 382: 61.59
+	Hs
		683276 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		KPCE_HUMAN (64-492): 8.86e-126: 388: 21.04
+	Mm
		554936 1433B_MOUSE (1-239): 3.73e-99: 290: 68.62		KPCE_MOUSE (64-507): 7.16e-126: 389: 20.79
+	Hs
		683541 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		KKCC1_HUMAN (61-536): 2.29e-126: 382: 61.59
+	Rn
		716562 1433B_RAT (1-239): 5.05e-100: 293: 69.04		KKCC1_RAT (71-536): 7.59e-126: 381: 63.11
+	Sp
		788705 RAD24_SCHPO (2-248): 5.1e-136: 385: 54.66		SSP1_SCHPO (162-481): 3.69e-61: 216: 40.77
+	Zm
		31741 A0A1D6KKP0_MAIZE (1-247): 6.14e-142: 399: 57.83		B4FIX4_MAIZE (162-455): 1.36e-50: 182: 39.32