HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: TSSK1 (Q9BXA7)
Testis-specific serine/threonine-protein kinase 1 (TSK-1) (TSK1) (TSSK-1) (Testis-specific kinase 1) (EC 2.7.11.1) (Serine/threonine-protein kinase 22A)
Gene: TSSK1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 367
+	Hs
		684274 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		TSSK2_HUMAN (1-352): 3.05e-145: 416: 68.27
+	Hs
		681682 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		AKT1_HUMAN (4-349): 6.92e-135: 395: 26.35
+	Hs
		909927 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TSSK2_HUMAN (1-352): 3.05e-145: 416: 68.27
+	At
		1280891 14337_ARATH (2-247): 4.35e-147: 413: 58.07		CIPKC_ARATH (2-365): 1.18e-140: 410: 29.40
+	At
		965360 14332_ARATH (3-248): 2.23e-144: 405: 58.47		CIPKC_ARATH (2-365): 1.18e-140: 410: 29.40
+	Hs
		681770 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AKT1_HUMAN (4-349): 6.92e-135: 395: 26.35
+	Hs
		909980 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		TSSK1_HUMAN (1-367): 1.04e-136: 395: 100.00
+	Xl
		223344 O57468_XENLA (2-246): 5.73e-145: 407: 60.00		Q804T2_XENLA (11-272): 2.01e-123: 373: 39.31
+	Hs
		683925 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK1_HUMAN (18-273): 9.41e-58: 202: 45.31
+	Hs
		684412 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK3_HUMAN (12-273): 2.18e-53: 191: 40.91
+	Hs
		684316 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SIK2_HUMAN (18-272): 4.54e-52: 187: 43.14
+	Hs
		647836 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK3_HUMAN (12-272): 8.19e-52: 185: 39.54
+	Hs
		684157 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK2_HUMAN (12-272): 3.69e-51: 184: 39.54
+	Hs
		883214 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SIK1_HUMAN (18-273): 9.41e-58: 202: 45.31
+	Hs
		910187 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SIK3_HUMAN (12-273): 2.18e-53: 191: 40.91
+	Hs
		910013 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SIK2_HUMAN (18-272): 4.54e-52: 187: 43.14
+	Hs
		647862 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK3_HUMAN (12-272): 8.19e-52: 185: 39.54
+	Hs
		909730 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK2_HUMAN (12-272): 3.69e-51: 184: 39.54
+	Mm
		910231 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK3_MOUSE (12-272): 4.23e-51: 183: 39.16
+	Xl
		223345 O57468_XENLA (2-246): 5.73e-145: 407: 60.00		Q8QGV3_XENLA (12-272): 2.9e-51: 184: 39.16