HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 759
+	Hs
		910129 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		927629 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		647361 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		683794 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		905224 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		982595 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		150530 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		909807 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		927298 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150550 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		684040 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00
+	Hs
		150553 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		683538 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		904849 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150524 1433T_HUMAN (1-238): 9.98e-108: 312: 71.85		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		982269 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150529 1433B_HUMAN (1-239): 3.41e-100: 293: 68.62		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150547 1433G_HUMAN (1-242): 1.86e-98: 289: 65.16		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150558 1433F_HUMAN (2-242): 2.78e-96: 283: 64.20		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28