HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: DYR1B (Q9Y463)
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)
Gene: DYRK1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 629
+	Hs
		910197 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYR1B_HUMAN (1-629): 2.33e-171: 503: 100.00
+	Hs
		684022 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYR1A_HUMAN (19-594): 3.53e-135: 415: 63.57
+	Hs
		909539 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYR1A_HUMAN (19-594): 3.53e-135: 415: 63.57
+	Hs
		647836 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		MARK3_HUMAN (57-629): 1.59e-123: 384: 18.49
+	Mm
		910255 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DYR1A_MOUSE (4-594): 7e-135: 414: 62.31
+	Hs
		684347 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYRK4_HUMAN (4-542): 1.03e-119: 367: 32.22
+	Hs
		684246 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYRK2_HUMAN (9-492): 1.61e-117: 364: 34.09
+	Hs
		681682 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		AKT1_HUMAN (6-429): 7.87e-119: 363: 18.41
+	Hs
		414774 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK1_HUMAN (108-434): 4.87e-121: 362: 27.76
+	Hs
		683964 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		CDK3_HUMAN (108-388): 6.4e-118: 355: 26.75
+	Hs
		647862 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MARK3_HUMAN (57-629): 1.59e-123: 384: 18.49
+	Mm
		910231 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		MARK3_MOUSE (57-629): 9.11e-122: 380: 18.49
+	Hs
		910066 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYRK4_HUMAN (4-542): 1.03e-119: 367: 32.22
+	Xl
		223344 O57468_XENLA (2-246): 5.73e-145: 407: 60.00		Q804T2_XENLA (57-621): 4.86e-118: 369: 18.92
+	Hs
		909877 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYRK2_HUMAN (9-492): 1.61e-117: 364: 34.09
+	Hs
		681770 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		AKT1_HUMAN (6-429): 7.87e-119: 363: 18.41
+	Hs
		625306 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK2_HUMAN (108-376): 5.32e-119: 357: 27.82
+	Hs
		909447 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		CDK3_HUMAN (108-388): 6.4e-118: 355: 26.75
+	Hs
		684216 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		HIPK4_HUMAN (111-440): 1.6e-50: 186: 37.68
+	Hs
		909828 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		HIPK4_HUMAN (111-440): 1.6e-50: 186: 37.68